BRD-K64058329_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K64058329_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
FHL1 four and a half LIM domains 1
GSTA1 glutathione S-transferase alpha 1
HMOX1 heme oxygenase 1
IGHM immunoglobulin heavy constant mu
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MGLL monoglyceride lipase
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
RHOQ ras homolog family member Q
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
TCF4 transcription factor 4
TFF1 trefoil factor 1
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTB actin, beta
ASS1 argininosuccinate synthase 1
C6ORF48 chromosome 6 open reading frame 48
COL5A2 collagen, type V, alpha 2
DPP4 dipeptidyl-peptidase 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
MRPS31 mitochondrial ribosomal protein S31
MXRA5 matrix-remodelling associated 5
NMU neuromedin U
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SCN3A sodium channel, voltage gated, type III alpha subunit
SFRP4 secreted frizzled-related protein 4
TRIB2 tribbles pseudokinase 2