Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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133 genes differentially expressed following the BRD-K64634304_Retinoic acid_SKMEL28_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
CAST | calpastatin |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
COL4A1 | collagen, type IV, alpha 1 |
COLEC12 | collectin sub-family member 12 |
CPE | carboxypeptidase E |
CRABP1 | cellular retinoic acid binding protein 1 |
CRABP2 | cellular retinoic acid binding protein 2 |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CYBB | cytochrome b-245, beta polypeptide |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DLK1 | delta-like 1 homolog (Drosophila) |
DOK5 | docking protein 5 |
DPYSL3 | dihydropyrimidinase-like 3 |
ELANE | elastase, neutrophil expressed |
EPAS1 | endothelial PAS domain protein 1 |
FAM198B | family with sequence similarity 198, member B |
FGFR2 | fibroblast growth factor receptor 2 |
GNLY | granulysin |
HBB | hemoglobin, beta |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMOX1 | heme oxygenase 1 |
HYOU1 | hypoxia up-regulated 1 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
IL1R1 | interleukin 1 receptor, type I |
IPO13 | importin 13 |
KRT19 | keratin 19, type I |
LOC100272216 | uncharacterized LOC100272216 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MMP2 | matrix metallopeptidase 2 |
MT1M | metallothionein 1M |
NCAPD2 | non-SMC condensin I complex, subunit D2 |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
PAPD7 | PAP associated domain containing 7 |
PCSK1 | proprotein convertase subtilisin/kexin type 1 |
PDE10A | phosphodiesterase 10A |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
PXDN | peroxidasin |
RGS5 | regulator of G-protein signaling 5 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
TBX3 | T-box 3 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TLR4 | toll-like receptor 4 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMEM30B | transmembrane protein 30B |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TPD52 | tumor protein D52 |
XIST | X inactive specific transcript (non-protein coding) |
ZHX2 | zinc fingers and homeoboxes 2 |
ZNF117 | zinc finger protein 117 |
ZNF586 | zinc finger protein 586 |
Symbol | Name |
---|---|
ADCY1 | adenylate cyclase 1 (brain) |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
AK1 | adenylate kinase 1 |
AREG | amphiregulin |
ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
BST2 | bone marrow stromal cell antigen 2 |
C7 | complement component 7 |
CCNF | cyclin F |
CD59 | CD59 molecule, complement regulatory protein |
CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CLEC11A | C-type lectin domain family 11, member A |
CTSH | cathepsin H |
DAPK1 | death-associated protein kinase 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DEFB1 | defensin, beta 1 |
DUSP10 | dual specificity phosphatase 10 |
DUSP2 | dual specificity phosphatase 2 |
DUSP6 | dual specificity phosphatase 6 |
ECM1 | extracellular matrix protein 1 |
FABP7 | fatty acid binding protein 7, brain |
FAM216A | family with sequence similarity 216, member A |
FOLR1 | folate receptor 1 (adult) |
FXYD2 | FXYD domain containing ion transport regulator 2 |
FXYD5 | FXYD domain containing ion transport regulator 5 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
GLDC | glycine dehydrogenase (decarboxylating) |
GRB14 | growth factor receptor-bound protein 14 |
HLF | hepatic leukemia factor |
HLTF | helicase-like transcription factor |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LPL | lipoprotein lipase |
LZTFL1 | leucine zipper transcription factor-like 1 |
MATN2 | matrilin 2 |
MBP | myelin basic protein |
MCOLN1 | mucolipin 1 |
MET | MET proto-oncogene, receptor tyrosine kinase |
NFIB | nuclear factor I/B |
NOV | nephroblastoma overexpressed |
NPY1R | neuropeptide Y receptor Y1 |
NRN1 | neuritin 1 |
NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PLP1 | proteolipid protein 1 |
PRKCH | protein kinase C, eta |
PSIP1 | PC4 and SFRS1 interacting protein 1 |
PTER | phosphotriesterase related |
PTN | pleiotrophin |
PXMP2 | peroxisomal membrane protein 2, 22kDa |
RGS1 | regulator of G-protein signaling 1 |
RPIA | ribose 5-phosphate isomerase A |
RPL38 | ribosomal protein L38 |
RPS11 | ribosomal protein S11 |
SATB1 | SATB homeobox 1 |
SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
SLPI | secretory leukocyte peptidase inhibitor |
SORBS1 | sorbin and SH3 domain containing 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TNC | tenascin C |
TSPAN3 | tetraspanin 3 |