Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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140 genes differentially expressed following the BRD-K64634304_Retinoic acid_THP1_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADA | adenosine deaminase |
ADD3 | adducin 3 (gamma) |
AIF1 | allograft inflammatory factor 1 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
BCL2A1 | BCL2-related protein A1 |
CD24 | CD24 molecule |
CD34 | CD34 molecule |
CD52 | CD52 molecule |
CREG1 | cellular repressor of E1A-stimulated genes 1 |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CYB561 | cytochrome b561 |
CYTH1 | cytohesin 1 |
EIF5 | eukaryotic translation initiation factor 5 |
ELF4 | E74-like factor 4 (ets domain transcription factor) |
FTH1 | ferritin, heavy polypeptide 1 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GM2A | GM2 ganglioside activator |
GNAS | GNAS complex locus |
GSTP1 | glutathione S-transferase pi 1 |
GTF2E2 | general transcription factor IIE, polypeptide 2, beta 34kDa |
HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
HMOX1 | heme oxygenase 1 |
HOPX | HOP homeobox |
ICAM1 | intercellular adhesion molecule 1 |
IFI30 | interferon, gamma-inducible protein 30 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
ITGAV | integrin, alpha V |
JUP | junction plakoglobin |
KYNU | kynureninase |
LCK | LCK proto-oncogene, Src family tyrosine kinase |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LYN | LYN proto-oncogene, Src family tyrosine kinase |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MIR22HG | MIR22 host gene |
MREG | melanoregulin |
NCF1C | neutrophil cytosolic factor 1C pseudogene |
NCOA3 | nuclear receptor coactivator 3 |
NRIP1 | nuclear receptor interacting protein 1 |
NSG1 | neuron specific gene family member 1 |
PECR | peroxisomal trans-2-enoyl-CoA reductase |
PGD | phosphogluconate dehydrogenase |
PLAT | plasminogen activator, tissue |
PSAP | prosaposin |
QPCT | glutaminyl-peptide cyclotransferase |
RAB13 | RAB13, member RAS oncogene family |
RGS5 | regulator of G-protein signaling 5 |
RIT1 | Ras-like without CAAX 1 |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
SFTPA2 | surfactant protein A2 |
SFTPB | surfactant protein B |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
SMAD3 | SMAD family member 3 |
SNN | stannin |
STX1A | syntaxin 1A (brain) |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TLR4 | toll-like receptor 4 |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
TNIP1 | TNFAIP3 interacting protein 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
TREM1 | triggering receptor expressed on myeloid cells 1 |
TUSC3 | tumor suppressor candidate 3 |
Symbol | Name |
---|---|
AHNAK | AHNAK nucleoprotein |
AKAP12 | A kinase (PRKA) anchor protein 12 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BCL2 | B-cell CLL/lymphoma 2 |
CCDC86 | coiled-coil domain containing 86 |
CCDC92 | coiled-coil domain containing 92 |
CD44 | CD44 molecule (Indian blood group) |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CTGF | connective tissue growth factor |
EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
ETV5 | ets variant 5 |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FGF13 | fibroblast growth factor 13 |
GAS1 | growth arrest-specific 1 |
HOXA10 | homeobox A10 |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
IGFBP7 | insulin-like growth factor binding protein 7 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
INSR | insulin receptor |
KAZN | kazrin, periplakin interacting protein |
KDM4B | lysine (K)-specific demethylase 4B |
KIF5C | kinesin family member 5C |
LINC00341 | long intergenic non-protein coding RNA 341 |
MAOB | monoamine oxidase B |
MAPT | microtubule-associated protein tau |
MEF2C | myocyte enhancer factor 2C |
MT1E | metallothionein 1E |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NFIB | nuclear factor I/B |
NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
PARM1 | prostate androgen-regulated mucin-like protein 1 |
PDZRN3 | PDZ domain containing ring finger 3 |
PEG3 | paternally expressed 3 |
PER2 | period circadian clock 2 |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PMP22 | peripheral myelin protein 22 |
PON2 | paraoxonase 2 |
PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
PUS7 | pseudouridylate synthase 7 (putative) |
RCAN1 | regulator of calcineurin 1 |
RGS2 | regulator of G-protein signaling 2 |
RHOB | ras homolog family member B |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SACS | sacsin molecular chaperone |
SATB2 | SATB homeobox 2 |
SEPT10 | septin 10 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SFRP4 | secreted frizzled-related protein 4 |
SH3BP4 | SH3-domain binding protein 4 |
SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 |
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
SORD | sorbitol dehydrogenase |
SRPX | sushi-repeat containing protein, X-linked |
STC1 | stanniocalcin 1 |
STEAP3 | STEAP family member 3, metalloreductase |
TCF4 | transcription factor 4 |
TGFBR3 | transforming growth factor, beta receptor III |
TMEM106B | transmembrane protein 106B |
TNS1 | tensin 1 |
TRIB2 | tribbles pseudokinase 2 |
TRIM22 | tripartite motif containing 22 |
TRPS1 | trichorhinophalangeal syndrome I |
TUBB6 | tubulin, beta 6 class V |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
YBX3 | Y box binding protein 3 |
ZBTB16 | zinc finger and BTB domain containing 16 |