BRD-K64634304_Retinoic acid_VCAP_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K64634304_Retinoic acid_VCAP_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
AIM2 absent in melanoma 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAMBI BMP and activin membrane-bound inhibitor
DYNLT3 dynein, light chain, Tctex-type 3
HEATR1 HEAT repeat containing 1
HES1 hes family bHLH transcription factor 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITM2A integral membrane protein 2A
KRT15 keratin 15, type I
LGALS8 lectin, galactoside-binding, soluble, 8
MDFIC MyoD family inhibitor domain containing
MMP12 matrix metallopeptidase 12
NRIP1 nuclear receptor interacting protein 1
PPARG peroxisome proliferator-activated receptor gamma
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RPL38 ribosomal protein L38
SPINK1 serine peptidase inhibitor, Kazal type 1
STC2 stanniocalcin 2
TARBP1 TAR (HIV-1) RNA binding protein 1
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C7 complement component 7
CLDN10 claudin 10
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
PPA1 pyrophosphatase (inorganic) 1
ST7 suppression of tumorigenicity 7
TSPAN1 tetraspanin 1
Funding