Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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117 genes differentially expressed following the BRD-K64642496_-666_SW948_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADCY9 | adenylate cyclase 9 |
ATF3 | activating transcription factor 3 |
BEX4 | brain expressed, X-linked 4 |
CA4 | carbonic anhydrase IV |
CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
CAPG | capping protein (actin filament), gelsolin-like |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CD9 | CD9 molecule |
COL1A2 | collagen, type I, alpha 2 |
COL4A5 | collagen, type IV, alpha 5 |
CSNK2A2 | casein kinase 2, alpha prime polypeptide |
DCN | decorin |
DDIT4 | DNA-damage-inducible transcript 4 |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
DSP | desmoplakin |
FAM129A | family with sequence similarity 129, member A |
FHL1 | four and a half LIM domains 1 |
FHOD3 | formin homology 2 domain containing 3 |
G0S2 | G0/G1 switch 2 |
GAS6 | growth arrest-specific 6 |
GPNMB | glycoprotein (transmembrane) nmb |
HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL1R1 | interleukin 1 receptor, type I |
ISG15 | ISG15 ubiquitin-like modifier |
KRT19 | keratin 19, type I |
LAMP3 | lysosomal-associated membrane protein 3 |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LOXL1 | lysyl oxidase-like 1 |
LUM | lumican |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
MME | membrane metallo-endopeptidase |
MMP12 | matrix metallopeptidase 12 |
MMP9 | matrix metallopeptidase 9 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PHKG2 | phosphorylase kinase, gamma 2 (testis) |
PLAU | plasminogen activator, urokinase |
PPAP2B | phosphatidic acid phosphatase type 2B |
PTN | pleiotrophin |
PXDN | peroxidasin |
S100P | S100 calcium binding protein P |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
SPON2 | spondin 2, extracellular matrix protein |
STC2 | stanniocalcin 2 |
SULF1 | sulfatase 1 |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
THBS2 | thrombospondin 2 |
TIMP2 | TIMP metallopeptidase inhibitor 2 |
TMEM30B | transmembrane protein 30B |
TMSB15A | thymosin beta 15a |
TSC22D3 | TSC22 domain family, member 3 |
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
WNT5A | wingless-type MMTV integration site family, member 5A |
Symbol | Name |
---|---|
ACLY | ATP citrate lyase |
AK1 | adenylate kinase 1 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
CD59 | CD59 molecule, complement regulatory protein |
CDC42 | cell division cycle 42 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CSK | c-src tyrosine kinase |
CSRP1 | cysteine and glycine-rich protein 1 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CXCL13 | chemokine (C-X-C motif) ligand 13 |
CYTL1 | cytokine-like 1 |
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DYNLL1 | dynein, light chain, LC8-type 1 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FABP7 | fatty acid binding protein 7, brain |
FGFR4 | fibroblast growth factor receptor 4 |
FOLR1 | folate receptor 1 (adult) |
GLS | glutaminase |
GSTP1 | glutathione S-transferase pi 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HN1 | hematological and neurological expressed 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA8 | heat shock 70kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IGKC | immunoglobulin kappa constant |
IGKV1-5 | immunoglobulin kappa variable 1-5 |
IGL | immunoglobulin lambda locus |
IGLV2-23 | immunoglobulin lambda variable 2-23 |
KIAA0125 | KIAA0125 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
MAPK13 | mitogen-activated protein kinase 13 |
MARCKSL1 | MARCKS-like 1 |
MET | MET proto-oncogene, receptor tyrosine kinase |
NAP1L1 | nucleosome assembly protein 1-like 1 |
NUP98 | nucleoporin 98kDa |
PEBP1 | phosphatidylethanolamine binding protein 1 |
PLK1 | polo-like kinase 1 |
PROM1 | prominin 1 |
PRSS3 | protease, serine, 3 |
RBMS1 | RNA binding motif, single stranded interacting protein 1 |
RFK | riboflavin kinase |
RPL36 | ribosomal protein L36 |
RPL37A | ribosomal protein L37a |
SNRPF | small nuclear ribonucleoprotein polypeptide F |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TM4SF1 | transmembrane 4 L six family member 1 |
TPD52 | tumor protein D52 |
TRAPPC3 | trafficking protein particle complex 3 |
TSPAN3 | tetraspanin 3 |
TSPAN8 | tetraspanin 8 |
UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
UBE2S | ubiquitin-conjugating enzyme E2S |
VDAC1 | voltage-dependent anion channel 1 |
ZC3H13 | zinc finger CCCH-type containing 13 |