| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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162 genes differentially expressed following the BRD-K64642496_-666_U937_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANK2 | ankyrin 2, neuronal |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| CBS | cystathionine-beta-synthase |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CKM | creatine kinase, muscle |
| CLDN10 | claudin 10 |
| CPE | carboxypeptidase E |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRYAB | crystallin, alpha B |
| DAPK1 | death-associated protein kinase 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EVI2A | ecotropic viral integration site 2A |
| FAM129A | family with sequence similarity 129, member A |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GUSB | glucuronidase, beta |
| H2BFS | H2B histone family, member S (pseudogene) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H4H | histone cluster 1, H4h |
| HIST2H2BE | histone cluster 2, H2be |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFITM1 | interferon induced transmembrane protein 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KLHDC2 | kelch domain containing 2 |
| KLHL24 | kelch-like family member 24 |
| KLHL41 | kelch-like family member 41 |
| KRT19 | keratin 19, type I |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MEF2C | myocyte enhancer factor 2C |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NEB | nebulin |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NID2 | nidogen 2 (osteonidogen) |
| NLGN4X | neuroligin 4, X-linked |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLFM4 | olfactomedin 4 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PTN | pleiotrophin |
| RHOB | ras homolog family member B |
| RSAD2 | radical S-adenosyl methionine domain containing 2 |
| SELENBP1 | selenium binding protein 1 |
| TMOD1 | tropomodulin 1 |
| TNNC2 | troponin C type 2 (fast) |
| TSC22D1 | TSC22 domain family, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TTN | titin |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACOT9 | acyl-CoA thioesterase 9 |
| ACTN1 | actinin, alpha 1 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AIM1 | absent in melanoma 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BTG2 | BTG family, member 2 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CALU | calumenin |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CERS6 | ceramide synthase 6 |
| CES1 | carboxylesterase 1 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 |
| CTSB | cathepsin B |
| CTSC | cathepsin C |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYTL1 | cytokine-like 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DUSP4 | dual specificity phosphatase 4 |
| EFCAB14 | EF-hand calcium binding domain 14 |
| EGR3 | early growth response 3 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| FASTKD5 | FAST kinase domains 5 |
| FN1 | fibronectin 1 |
| HAL | histidine ammonia-lyase |
| HAT1 | histone acetyltransferase 1 |
| HDAC2 | histone deacetylase 2 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| IPO7 | importin 7 |
| IRS2 | insulin receptor substrate 2 |
| JADE2 | jade family PHD finger 2 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| LBR | lamin B receptor |
| LIMS1 | LIM and senescent cell antigen-like domains 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MEGF9 | multiple EGF-like-domains 9 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MSMB | microseminoprotein, beta- |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NARFL | nuclear prelamin A recognition factor-like |
| NFIB | nuclear factor I/B |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| NTS | neurotensin |
| PLAUR | plasminogen activator, urokinase receptor |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 |
| PLLP | plasmolipin |
| PPIF | peptidylprolyl isomerase F |
| PRKCB | protein kinase C, beta |
| PRKCD | protein kinase C, delta |
| RAB4A | RAB4A, member RAS oncogene family |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RPL31 | ribosomal protein L31 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORD | sorbitol dehydrogenase |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TARP | TCR gamma alternate reading frame protein |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOX3 | TOX high mobility group box family member 3 |
| TRIM14 | tripartite motif containing 14 |
| TUBB6 | tubulin, beta 6 class V |
| UBE3C | ubiquitin protein ligase E3C |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
