BRD-K64800655_PHA-793887_MDAMB231_24_h_0.04_um Gene Set
Genes
46 genes differentially expressed following the BRD-K64800655_PHA-793887_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
AKR1C3
|
aldo-keto reductase family 1, member C3
|
CX3CL1
|
chemokine (C-X3-C motif) ligand 1
|
DHCR24
|
24-dehydrocholesterol reductase
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
GSTM3
|
glutathione S-transferase mu 3 (brain)
|
GSTT1
|
glutathione S-transferase theta 1
|
HIST1H2AC
|
histone cluster 1, H2ac
|
HIST1H2BD
|
histone cluster 1, H2bd
|
IGFBP5
|
insulin-like growth factor binding protein 5
|
ITGA3
|
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
|
LDLR
|
low density lipoprotein receptor
|
MSMO1
|
methylsterol monooxygenase 1
|
NDNF
|
neuron-derived neurotrophic factor
|
NEU1
|
sialidase 1 (lysosomal sialidase)
|
OPN3
|
opsin 3
|
PDZK1IP1
|
PDZK1 interacting protein 1
|
QPRT
|
quinolinate phosphoribosyltransferase
|
SCNN1A
|
sodium channel, non voltage gated 1 alpha subunit
|
SEPP1
|
selenoprotein P, plasma, 1
|
SERPINE2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
|
SFN
|
stratifin
|
SLPI
|
secretory leukocyte peptidase inhibitor
|
VEGFA
|
vascular endothelial growth factor A
|
WSB1
|
WD repeat and SOCS box containing 1
|
decreased expression
Symbol |
Name |
AGR2
|
anterior gradient 2
|
BRCA1
|
breast cancer 1, early onset
|
CHEK2
|
checkpoint kinase 2
|
CILP
|
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
|
DCK
|
deoxycytidine kinase
|
EHF
|
ets homologous factor
|
ENPP2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
GMDS
|
GDP-mannose 4,6-dehydratase
|
HOXC6
|
homeobox C6
|
HSPA2
|
heat shock 70kDa protein 2
|
IL1R2
|
interleukin 1 receptor, type II
|
LTF
|
lactotransferrin
|
NNMT
|
nicotinamide N-methyltransferase
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
RRM2
|
ribonucleotide reductase M2
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family)
|
TESC
|
tescalcin
|
TFF3
|
trefoil factor 3 (intestinal)
|
THBS2
|
thrombospondin 2
|
TMEM158
|
transmembrane protein 158 (gene/pseudogene)
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|