Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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90 genes differentially expressed following the BRD-K64857848_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
CCDC85B | coiled-coil domain containing 85B |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CFD | complement factor D (adipsin) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CLU | clusterin |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DAPK1 | death-associated protein kinase 1 |
DHCR24 | 24-dehydrocholesterol reductase |
EAF2 | ELL associated factor 2 |
EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EPAS1 | endothelial PAS domain protein 1 |
GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HIST1H2BK | histone cluster 1, H2bk |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HSPA2 | heat shock 70kDa protein 2 |
IFI6 | interferon, alpha-inducible protein 6 |
IL16 | interleukin 16 |
KIAA1033 | KIAA1033 |
LPIN1 | lipin 1 |
MAP1B | microtubule-associated protein 1B |
MSMO1 | methylsterol monooxygenase 1 |
MT1X | metallothionein 1X |
MZB1 | marginal zone B and B1 cell-specific protein |
NLRP2 | NLR family, pyrin domain containing 2 |
ORM1 | orosomucoid 1 |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PEG3 | paternally expressed 3 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
RPL37A | ribosomal protein L37a |
RPL38 | ribosomal protein L38 |
S100A9 | S100 calcium binding protein A9 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SELL | selectin L |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
TF | transferrin |
TUBA1A | tubulin, alpha 1a |
TUBA4A | tubulin, alpha 4a |
TXN | thioredoxin |
VWA5A | von Willebrand factor A domain containing 5A |
ZBTB18 | zinc finger and BTB domain containing 18 |
Symbol | Name |
---|---|
ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CST1 | cystatin SN |
DACH1 | dachshund family transcription factor 1 |
ECI2 | enoyl-CoA delta isomerase 2 |
ELOVL6 | ELOVL fatty acid elongase 6 |
FAM3C | family with sequence similarity 3, member C |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GDF15 | growth differentiation factor 15 |
GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
GSAP | gamma-secretase activating protein |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
H1F0 | H1 histone family, member 0 |
HOXC6 | homeobox C6 |
IGFBP3 | insulin-like growth factor binding protein 3 |
JADE2 | jade family PHD finger 2 |
LEF1 | lymphoid enhancer-binding factor 1 |
MOK | MOK protein kinase |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NRN1 | neuritin 1 |
PAM | peptidylglycine alpha-amidating monooxygenase |
PDAP1 | PDGFA associated protein 1 |
PICALM | phosphatidylinositol binding clathrin assembly protein |
PLAT | plasminogen activator, tissue |
PPARG | peroxisome proliferator-activated receptor gamma |
PRSS23 | protease, serine, 23 |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
RAD23B | RAD23 homolog B (S. cerevisiae) |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
SPRY2 | sprouty homolog 2 (Drosophila) |
SRI | sorcin |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TFPI2 | tissue factor pathway inhibitor 2 |
TIMP1 | TIMP metallopeptidase inhibitor 1 |
TLR4 | toll-like receptor 4 |
TMEM176B | transmembrane protein 176B |
TPBG | trophoblast glycoprotein |
TWIST1 | twist family bHLH transcription factor 1 |
VCAM1 | vascular cell adhesion molecule 1 |
VCAN | versican |
WNT5A | wingless-type MMTV integration site family, member 5A |