Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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102 genes differentially expressed following the BRD-K64890080_BI-2536_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AK1 | adenylate kinase 1 |
ATF3 | activating transcription factor 3 |
BTG2 | BTG family, member 2 |
C8ORF4 | chromosome 8 open reading frame 4 |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CD9 | CD9 molecule |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CLDN10 | claudin 10 |
CTSK | cathepsin K |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DUSP2 | dual specificity phosphatase 2 |
DUSP5 | dual specificity phosphatase 5 |
FBLN1 | fibulin 1 |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
GADD45B | growth arrest and DNA-damage-inducible, beta |
H2BFS | H2B histone family, member S (pseudogene) |
HIST1H1C | histone cluster 1, H1c |
HIST1H2AC | histone cluster 1, H2ac |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H3H | histone cluster 1, H3h |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
IER5 | immediate early response 5 |
KLF4 | Kruppel-like factor 4 (gut) |
LOC100505650 | uncharacterized LOC100505650 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
NBL1 | neuroblastoma 1, DAN family BMP antagonist |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
RGS2 | regulator of G-protein signaling 2 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SIK1 | salt-inducible kinase 1 |
SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
SPON1 | spondin 1, extracellular matrix protein |
STAP2 | signal transducing adaptor family member 2 |
TFRC | transferrin receptor |
ZFP36 | ZFP36 ring finger protein |
ZNF331 | zinc finger protein 331 |
Symbol | Name |
---|---|
ACSL1 | acyl-CoA synthetase long-chain family member 1 |
ADGRG2 | adhesion G protein-coupled receptor G2 |
ADIPOQ | adiponectin, C1Q and collagen domain containing |
ALCAM | activated leukocyte cell adhesion molecule |
AMOTL2 | angiomotin like 2 |
ANXA1 | annexin A1 |
APOD | apolipoprotein D |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
ATF1 | activating transcription factor 1 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
AZU1 | azurocidin 1 |
BEX1 | brain expressed, X-linked 1 |
CCL2 | chemokine (C-C motif) ligand 2 |
CFD | complement factor D (adipsin) |
CPD | carboxypeptidase D |
CSTA | cystatin A (stefin A) |
CTSG | cathepsin G |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
ELANE | elastase, neutrophil expressed |
EREG | epiregulin |
F5 | coagulation factor V (proaccelerin, labile factor) |
FNDC3B | fibronectin type III domain containing 3B |
FXYD5 | FXYD domain containing ion transport regulator 5 |
HOXA10 | homeobox A10 |
HOXB6 | homeobox B6 |
IRS2 | insulin receptor substrate 2 |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
KRT18 | keratin 18, type I |
LYPLA1 | lysophospholipase I |
MAP1B | microtubule-associated protein 1B |
MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
MNDA | myeloid cell nuclear differentiation antigen |
MPO | myeloperoxidase |
MRPS18B | mitochondrial ribosomal protein S18B |
MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
MX2 | MX dynamin-like GTPase 2 |
NPTX2 | neuronal pentraxin II |
PLA2G16 | phospholipase A2, group XVI |
PLAC8 | placenta-specific 8 |
PRPF4 | pre-mRNA processing factor 4 |
PUF60 | poly-U binding splicing factor 60KDa |
RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
RNASE3 | ribonuclease, RNase A family, 3 |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
S100P | S100 calcium binding protein P |
SEC61G | Sec61 gamma subunit |
SELL | selectin L |
SNRPE | small nuclear ribonucleoprotein polypeptide E |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SPRED2 | sprouty-related, EVH1 domain containing 2 |
SRGN | serglycin |
SUB1 | SUB1 homolog (S. cerevisiae) |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TARP | TCR gamma alternate reading frame protein |
TFPI2 | tissue factor pathway inhibitor 2 |
TLR4 | toll-like receptor 4 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TNS3 | tensin 3 |