| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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189 genes differentially expressed following the BRD-K64890080_BI-2536_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| ALB | albumin |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALDOC | aldolase C, fructose-bisphosphate |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CD9 | CD9 molecule |
| CDC42 | cell division cycle 42 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CIRBP | cold inducible RNA binding protein |
| CLC | Charcot-Leyden crystal galectin |
| CLIC5 | chloride intracellular channel 5 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CORO1C | coronin, actin binding protein, 1C |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DENND1B | DENN/MADD domain containing 1B |
| DMBT1 | deleted in malignant brain tumors 1 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DUSP5 | dual specificity phosphatase 5 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EZR | ezrin |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FN1 | fibronectin 1 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS | glutaminase |
| GM2A | GM2 ganglioside activator |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| H2BFS | H2B histone family, member S (pseudogene) |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HEBP1 | heme binding protein 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| IER5 | immediate early response 5 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| ITGB4 | integrin, beta 4 |
| KIF2C | kinesin family member 2C |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LCN2 | lipocalin 2 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LTF | lactotransferrin |
| LYZ | lysozyme |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MTSS1 | metastasis suppressor 1 |
| NCAM1 | neural cell adhesion molecule 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLFM4 | olfactomedin 4 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDH9 | protocadherin 9 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RGS13 | regulator of G-protein signaling 13 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SYT1 | synaptotagmin I |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TKTL1 | transketolase-like 1 |
| TMEM2 | transmembrane protein 2 |
| TSPAN13 | tetraspanin 13 |
| TUBA1A | tubulin, alpha 1a |
| TUBB6 | tubulin, beta 6 class V |
| TXNIP | thioredoxin interacting protein |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| AK2 | adenylate kinase 2 |
| ASPN | asporin |
| ATF1 | activating transcription factor 1 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BST2 | bone marrow stromal cell antigen 2 |
| C1S | complement component 1, s subcomponent |
| C3 | complement component 3 |
| CA12 | carbonic anhydrase XII |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CDK4 | cyclin-dependent kinase 4 |
| COL15A1 | collagen, type XV, alpha 1 |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CPE | carboxypeptidase E |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| EFS | embryonal Fyn-associated substrate |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| FAP | fibroblast activation protein, alpha |
| FBLN1 | fibulin 1 |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT3 | fms-related tyrosine kinase 3 |
| FMOD | fibromodulin |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| GAS1 | growth arrest-specific 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GGCT | gamma-glutamylcyclotransferase |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXB7 | homeobox B7 |
| HSPB8 | heat shock 22kDa protein 8 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| INHBB | inhibin, beta B |
| ITGA7 | integrin, alpha 7 |
| ITM2A | integral membrane protein 2A |
| KRT17 | keratin 17, type I |
| KRT18 | keratin 18, type I |
| LOX | lysyl oxidase |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MBP | myelin basic protein |
| MRPL3 | mitochondrial ribosomal protein L3 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTA1 | metastasis associated 1 |
| MXRA5 | matrix-remodelling associated 5 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle |
| NDRG2 | NDRG family member 2 |
| NNMT | nicotinamide N-methyltransferase |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDZD2 | PDZ domain containing 2 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PLAC8 | placenta-specific 8 |
| POSTN | periostin, osteoblast specific factor |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPIF | peptidylprolyl isomerase F |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PRDX2 | peroxiredoxin 2 |
| PRKCH | protein kinase C, eta |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCAN1 | regulator of calcineurin 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RGS5 | regulator of G-protein signaling 5 |
| RNF167 | ring finger protein 167 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCP2 | sterol carrier protein 2 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SFN | stratifin |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC35F2 | solute carrier family 35, member F2 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPON1 | spondin 1, extracellular matrix protein |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM109 | transmembrane protein 109 |
| TMEM97 | transmembrane protein 97 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TSPAN4 | tetraspanin 4 |
| TSPAN8 | tetraspanin 8 |
| VCAN | versican |
| XBP1 | X-box binding protein 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
