BRD-K65093687_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K65093687_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD93 CD93 molecule
CDC42 cell division cycle 42
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP4A charged multivesicular body protein 4A
CNN3 calponin 3, acidic
FADS1 fatty acid desaturase 1
FGFR2 fibroblast growth factor receptor 2
FKBP4 FK506 binding protein 4, 59kDa
FN1 fibronectin 1
GJA1 gap junction protein, alpha 1, 43kDa
H1F0 H1 histone family, member 0
HAPLN1 hyaluronan and proteoglycan link protein 1
IGFBP5 insulin-like growth factor binding protein 5
JAG1 jagged 1
LOC100505650 uncharacterized LOC100505650
PDE4B phosphodiesterase 4B, cAMP-specific
PSAT1 phosphoserine aminotransferase 1
SCGB1D2 secretoglobin, family 1D, member 2
SERINC5 serine incorporator 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC35F2 solute carrier family 35, member F2
SRGN serglycin
SUSD4 sushi domain containing 4
TFPI2 tissue factor pathway inhibitor 2
TMEM47 transmembrane protein 47

decreased expression

Symbol Name
CD59 CD59 molecule, complement regulatory protein
CHL1 cell adhesion molecule L1-like
CLU clusterin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
LAPTM4B lysosomal protein transmembrane 4 beta
MARCKS myristoylated alanine-rich protein kinase C substrate
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PFN2 profilin 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
SEPP1 selenoprotein P, plasma, 1
ZIC1 Zic family member 1