Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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86 genes differentially expressed following the BRD-K65182930_NVP-AUY922_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
AURKA | aurora kinase A |
AUTS2 | autism susceptibility candidate 2 |
BRD4 | bromodomain containing 4 |
CBS | cystathionine-beta-synthase |
CDH3 | cadherin 3, type 1, P-cadherin (placental) |
CFB | complement factor B |
CRYAB | crystallin, alpha B |
DAPK1 | death-associated protein kinase 1 |
DHCR24 | 24-dehydrocholesterol reductase |
DLG5 | discs, large homolog 5 (Drosophila) |
DOK5 | docking protein 5 |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
GPC3 | glypican 3 |
GPR143 | G protein-coupled receptor 143 |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HSPA1A | heat shock 70kDa protein 1A |
HSPB8 | heat shock 22kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
ITM2C | integral membrane protein 2C |
KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
KIAA0125 | KIAA0125 |
LITAF | lipopolysaccharide-induced TNF factor |
MAGED1 | melanoma antigen family D1 |
MAP1A | microtubule-associated protein 1A |
MSMO1 | methylsterol monooxygenase 1 |
MYH10 | myosin, heavy chain 10, non-muscle |
MYLK | myosin light chain kinase |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
RGS2 | regulator of G-protein signaling 2 |
RPL31 | ribosomal protein L31 |
SDC2 | syndecan 2 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SQLE | squalene epoxidase |
SST | somatostatin |
Symbol | Name |
---|---|
ADM | adrenomedullin |
ADRB2 | adrenoceptor beta 2, surface |
ANXA3 | annexin A3 |
AXL | AXL receptor tyrosine kinase |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CDC25A | cell division cycle 25A |
CDCP1 | CUB domain containing protein 1 |
COTL1 | coactosin-like F-actin binding protein 1 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DNMBP | dynamin binding protein |
DUSP4 | dual specificity phosphatase 4 |
DUSP6 | dual specificity phosphatase 6 |
EFHD2 | EF-hand domain family, member D2 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FN1 | fibronectin 1 |
FOSL1 | FOS-like antigen 1 |
FXYD3 | FXYD domain containing ion transport regulator 3 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GINS2 | GINS complex subunit 2 (Psf2 homolog) |
HBEGF | heparin-binding EGF-like growth factor |
HPCAL1 | hippocalcin-like 1 |
IER3 | immediate early response 3 |
IGFBP7 | insulin-like growth factor binding protein 7 |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
MALL | mal, T-cell differentiation protein-like |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MCM3 | minichromosome maintenance complex component 3 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PLAC8 | placenta-specific 8 |
PLAU | plasminogen activator, urokinase |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PRF1 | perforin 1 (pore forming protein) |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RHOBTB3 | Rho-related BTB domain containing 3 |
RRM2 | ribonucleotide reductase M2 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
SRPX | sushi-repeat containing protein, X-linked |
TGFA | transforming growth factor, alpha |
TSPAN7 | tetraspanin 7 |