BRD-K65366129_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

42 genes differentially expressed following the BRD-K65366129_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSM3 acyl-CoA synthetase medium-chain family member 3
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
COL8A2 collagen, type VIII, alpha 2
CX3CL1 chemokine (C-X3-C motif) ligand 1
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
GSN gelsolin
IGFBP5 insulin-like growth factor binding protein 5
LDOC1 leucine zipper, down-regulated in cancer 1
MGLL monoglyceride lipase
MT1F metallothionein 1F
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRNP prion protein
QPCT glutaminyl-peptide cyclotransferase
SLC38A1 solute carrier family 38, member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
AIM2 absent in melanoma 2
BCL6 B-cell CLL/lymphoma 6
CCND1 cyclin D1
CCNG1 cyclin G1
CNPY3 canopy FGF signaling regulator 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTTN cortactin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FAM46A family with sequence similarity 46, member A
IFI16 interferon, gamma-inducible protein 16
MARCKS myristoylated alanine-rich protein kinase C substrate
MSLN mesothelin
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRDX2 peroxiredoxin 2
RPL37A ribosomal protein L37a
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa