BRD-K65503129_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

16 genes differentially expressed following the BRD-K65503129_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
BHLHE41 basic helix-loop-helix family, member e41
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
KCTD12 potassium channel tetramerization domain containing 12
RGS2 regulator of G-protein signaling 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
CCNB2 cyclin B2
IER3 immediate early response 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2