BRD-K65814004_Diphenyleneiodonium chloride_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

152 genes differentially expressed following the BRD-K65814004_Diphenyleneiodonium chloride_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACADVL acyl-CoA dehydrogenase, very long chain
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF5 activating transcription factor 5
ATPIF1 ATPase inhibitory factor 1
BAMBI BMP and activin membrane-bound inhibitor
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C8ORF4 chromosome 8 open reading frame 4
CA11 carbonic anhydrase XI
CCDC69 coiled-coil domain containing 69
CCND3 cyclin D3
CD163 CD163 molecule
CDK19 cyclin-dependent kinase 19
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COX17 COX17 cytochrome c oxidase copper chaperone
CXCL14 chemokine (C-X-C motif) ligand 14
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDB2 damage-specific DNA binding protein 2, 48kDa
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ENO2 enolase 2 (gamma, neuronal)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FUCA1 fucosidase, alpha-L- 1, tissue
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
GOLGA8A golgin A8 family, member A
GRN granulin
HAT1 histone acetyltransferase 1
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LAMP3 lysosomal-associated membrane protein 3
LIMCH1 LIM and calponin homology domains 1
MEGF9 multiple EGF-like-domains 9
MYO6 myosin VI
NRN1 neuritin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAX5 paired box 5
PFKM phosphofructokinase, muscle
PI3 peptidase inhibitor 3, skin-derived
PLCB4 phospholipase C, beta 4
PLS1 plastin 1
PNMA2 paraneoplastic Ma antigen 2
PRAME preferentially expressed antigen in melanoma
PRKCB protein kinase C, beta
PTPRE protein tyrosine phosphatase, receptor type, E
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
S100A8 S100 calcium binding protein A8
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPAG4 sperm associated antigen 4
SPRR1B small proline-rich protein 1B
SSBP2 single-stranded DNA binding protein 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TCEA2 transcription elongation factor A (SII), 2
TFPI2 tissue factor pathway inhibitor 2
TPD52 tumor protein D52
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAV3 vav 3 guanine nucleotide exchange factor
WIF1 WNT inhibitory factor 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AEBP1 AE binding protein 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
BGN biglycan
BZW2 basic leucine zipper and W2 domains 2
CALB1 calbindin 1, 28kDa
CALD1 caldesmon 1
CALML5 calmodulin-like 5
CAPG capping protein (actin filament), gelsolin-like
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CBR3 carbonyl reductase 3
CD58 CD58 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKAP4 cytoskeleton-associated protein 4
COL14A1 collagen, type XIV, alpha 1
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COMP cartilage oligomeric matrix protein
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DEFB1 defensin, beta 1
DPYSL3 dihydropyrimidinase-like 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHF ets homologous factor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
FAP fibroblast activation protein, alpha
FBN1 fibrillin 1
FN1 fibronectin 1
GAS6 growth arrest-specific 6
GBP1 guanylate binding protein 1, interferon-inducible
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
KCTD12 potassium channel tetramerization domain containing 12
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LRRC17 leucine rich repeat containing 17
MARCKS myristoylated alanine-rich protein kinase C substrate
MCUR1 mitochondrial calcium uniporter regulator 1
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MINA MYC induced nuclear antigen
MSLN mesothelin
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV3 neuron navigator 3
OLFML3 olfactomedin-like 3
PALLD palladin, cytoskeletal associated protein
PDLIM5 PDZ and LIM domain 5
PEA15 phosphoprotein enriched in astrocytes 15
PHGDH phosphoglycerate dehydrogenase
PLAU plasminogen activator, urokinase
PPAP2B phosphatidic acid phosphatase type 2B
PRKCDBP protein kinase C, delta binding protein
PRRX1 paired related homeobox 1
PSAT1 phosphoserine aminotransferase 1
PTRF polymerase I and transcript release factor
PWP1 PWP1 homolog (S. cerevisiae)
PYCR1 pyrroline-5-carboxylate reductase 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPL38 ribosomal protein L38
RSU1 Ras suppressor protein 1
S100A6 S100 calcium binding protein A6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPT11 septin 11
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP4 secreted frizzled-related protein 4
SNAI2 snail family zinc finger 2
SORD sorbitol dehydrogenase
SQLE squalene epoxidase
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
UCK2 uridine-cytidine kinase 2
VCAM1 vascular cell adhesion molecule 1