BRD-K65814004_Diphenyleneiodonium chloride_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

119 genes differentially expressed following the BRD-K65814004_Diphenyleneiodonium chloride_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACBD3 acyl-CoA binding domain containing 3
ACKR3 atypical chemokine receptor 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADD3 adducin 3 (gamma)
AK4 adenylate kinase 4
ANXA10 annexin A10
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD24 CD24 molecule
CD9 CD9 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CELF2 CUGBP, Elav-like family member 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COMP cartilage oligomeric matrix protein
CTSE cathepsin E
CXCL14 chemokine (C-X-C motif) ligand 14
CYBRD1 cytochrome b reductase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EMP1 epithelial membrane protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ESR1 estrogen receptor 1
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM198B family with sequence similarity 198, member B
FKBP14 FK506 binding protein 14, 22 kDa
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GSTM3 glutathione S-transferase mu 3 (brain)
HDAC9 histone deacetylase 9
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6ST interleukin 6 signal transducer
KDM4B lysine (K)-specific demethylase 4B
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LTF lactotransferrin
MIR22HG MIR22 host gene
MMP13 matrix metallopeptidase 13
MYO6 myosin VI
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPY1R neuropeptide Y receptor Y1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM4 olfactomedin 4
PDGFA platelet-derived growth factor alpha polypeptide
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PNMA2 paraneoplastic Ma antigen 2
PTTG1IP pituitary tumor-transforming 1 interacting protein
PTX3 pentraxin 3, long
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
SRRM2 serine/arginine repetitive matrix 2
TFF1 trefoil factor 1
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNIP1 TNFAIP3 interacting protein 1
TRIB3 tribbles pseudokinase 3
UGDH UDP-glucose 6-dehydrogenase
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
BPIFA1 BPI fold containing family A, member 1
BZW2 basic leucine zipper and W2 domains 2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD200 CD200 molecule
CHL1 cell adhesion molecule L1-like
CX3CR1 chemokine (C-X3-C motif) receptor 1
DEFB1 defensin, beta 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPN2 epsin 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GRSF1 G-rich RNA sequence binding factor 1
HOPX HOP homeobox
HSPA8 heat shock 70kDa protein 8
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITM2A integral membrane protein 2A
KIF20A kinesin family member 20A
LYPD3 LY6/PLAUR domain containing 3
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MEF2C myocyte enhancer factor 2C
MEIS1 Meis homeobox 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NID2 nidogen 2 (osteonidogen)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLK1 polo-like kinase 1
RELN reelin
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SMAGP small cell adhesion glycoprotein
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TGM2 transglutaminase 2
TMEM5 transmembrane protein 5
TNNT1 troponin T type 1 (skeletal, slow)
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
VAV3 vav 3 guanine nucleotide exchange factor