BRD-K65814004_Diphenyleneiodonium chloride_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K65814004_Diphenyleneiodonium chloride_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA2 carbonic anhydrase II
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRABP1 cellular retinoic acid binding protein 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
EFNA1 ephrin-A1
EGLN3 egl-9 family hypoxia-inducible factor 3
F2RL1 coagulation factor II (thrombin) receptor-like 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HOPX HOP homeobox
KDM3A lysine (K)-specific demethylase 3A
KLF4 Kruppel-like factor 4 (gut)
KRT6B keratin 6B, type II
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NDRG1 N-myc downstream regulated 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI2 peptidyl arginine deiminase, type II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFA platelet-derived growth factor alpha polypeptide
PDZK1IP1 PDZK1 interacting protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PI3 peptidase inhibitor 3, skin-derived
PLAT plasminogen activator, tissue
PXDN peroxidasin
RIOK3 RIO kinase 3
S100A7 S100 calcium binding protein A7
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TCEA2 transcription elongation factor A (SII), 2
TNIP1 TNFAIP3 interacting protein 1
TOX3 TOX high mobility group box family member 3
TPBG trophoblast glycoprotein
TRIB2 tribbles pseudokinase 2
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOD apolipoprotein D
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GPX2 glutathione peroxidase 2
LAMB1 laminin, beta 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBR3 transforming growth factor, beta receptor III
TMEM5 transmembrane protein 5
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa