BRD-K65814004_Diphenyleneiodonium chloride_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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46 genes differentially expressed following the BRD-K65814004_Diphenyleneiodonium chloride_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
DDIT4 DNA-damage-inducible transcript 4
PRKCH protein kinase C, eta
SFTPB surfactant protein B
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TARP TCR gamma alternate reading frame protein
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASPH aspartate beta-hydroxylase
ATM ATM serine/threonine kinase
BTG1 B-cell translocation gene 1, anti-proliferative
COG7 component of oligomeric golgi complex 7
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CREB1 cAMP responsive element binding protein 1
CSTA cystatin A (stefin A)
CYBRD1 cytochrome b reductase 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ECI1 enoyl-CoA delta isomerase 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP4 fatty acid binding protein 4, adipocyte
FBXL12 F-box and leucine-rich repeat protein 12
FN1 fibronectin 1
GRB7 growth factor receptor-bound protein 7
HNMT histamine N-methyltransferase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL1B interleukin 1, beta
JAG1 jagged 1
KRT81 keratin 81, type II
MRPL12 mitochondrial ribosomal protein L12
NPIPB3 nuclear pore complex interacting protein family, member B3
PPAP2B phosphatidic acid phosphatase type 2B
REG1A regenerating islet-derived 1 alpha
RTN2 reticulon 2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SOX11 SRY (sex determining region Y)-box 11
SOX9 SRY (sex determining region Y)-box 9
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TMSB15B thymosin beta 15B
TP53I3 tumor protein p53 inducible protein 3
TSPAN4 tetraspanin 4
VGLL4 vestigial-like family member 4