Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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85 genes differentially expressed following the BRD-K66296774_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
BST2 | bone marrow stromal cell antigen 2 |
C8ORF4 | chromosome 8 open reading frame 4 |
CD99 | CD99 molecule |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CLU | clusterin |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DMD | dystrophin |
EDN3 | endothelin 3 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FOLR1 | folate receptor 1 (adult) |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GBP2 | guanylate binding protein 2, interferon-inducible |
HMOX1 | heme oxygenase 1 |
HOPX | HOP homeobox |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IGFBP6 | insulin-like growth factor binding protein 6 |
JUN | jun proto-oncogene |
LY6D | lymphocyte antigen 6 complex, locus D |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MMP12 | matrix metallopeptidase 12 |
NEFL | neurofilament, light polypeptide |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
NT5DC2 | 5'-nucleotidase domain containing 2 |
PEG3 | paternally expressed 3 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PMP2 | peripheral myelin protein 2 |
PRKCD | protein kinase C, delta |
RHOBTB3 | Rho-related BTB domain containing 3 |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TNNT1 | troponin T type 1 (skeletal, slow) |
Symbol | Name |
---|---|
AGTR1 | angiotensin II receptor, type 1 |
ALCAM | activated leukocyte cell adhesion molecule |
ARHGAP29 | Rho GTPase activating protein 29 |
ATG3 | autophagy related 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CBX3 | chromobox homolog 3 |
CCND1 | cyclin D1 |
CD200 | CD200 molecule |
CD38 | CD38 molecule |
CP | ceruloplasmin (ferroxidase) |
CPE | carboxypeptidase E |
CTGF | connective tissue growth factor |
DCLK1 | doublecortin-like kinase 1 |
DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
DEFB1 | defensin, beta 1 |
DHCR24 | 24-dehydrocholesterol reductase |
DUSP6 | dual specificity phosphatase 6 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
FADS1 | fatty acid desaturase 1 |
FGG | fibrinogen gamma chain |
G0S2 | G0/G1 switch 2 |
GPX7 | glutathione peroxidase 7 |
HDAC9 | histone deacetylase 9 |
HIST1H2BD | histone cluster 1, H2bd |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
KLK11 | kallikrein-related peptidase 11 |
KRT23 | keratin 23, type I |
MOK | MOK protein kinase |
MSMO1 | methylsterol monooxygenase 1 |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NPTX2 | neuronal pentraxin II |
NTS | neurotensin |
NUAK1 | NUAK family, SNF1-like kinase, 1 |
PEG10 | paternally expressed 10 |
PRSS23 | protease, serine, 23 |
QPCT | glutaminyl-peptide cyclotransferase |
RGS2 | regulator of G-protein signaling 2 |
SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
SLC38A2 | solute carrier family 38, member 2 |
SMAD3 | SMAD family member 3 |
SRSF6 | serine/arginine-rich splicing factor 6 |
TBPL1 | TBP-like 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TFRC | transferrin receptor |
THBS2 | thrombospondin 2 |
THY1 | Thy-1 cell surface antigen |
TMPRSS3 | transmembrane protease, serine 3 |
VCAM1 | vascular cell adhesion molecule 1 |