BRD-K66707493_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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32 genes differentially expressed following the BRD-K66707493_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
APMAP adipocyte plasma membrane associated protein
AREG amphiregulin
C1QA complement component 1, q subcomponent, A chain
CAV1 caveolin 1, caveolae protein, 22kDa
H2AFV H2A histone family, member V
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
L1CAM L1 cell adhesion molecule
PDGFC platelet derived growth factor C
PMP22 peripheral myelin protein 22
SRGN serglycin
TFPI2 tissue factor pathway inhibitor 2

decreased expression

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
BASP1 brain abundant, membrane attached signal protein 1
BHLHE41 basic helix-loop-helix family, member e41
CYBA cytochrome b-245, alpha polypeptide
ECM1 extracellular matrix protein 1
EGR3 early growth response 3
ESRP1 epithelial splicing regulatory protein 1
FGF13 fibroblast growth factor 13
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
QPCT glutaminyl-peptide cyclotransferase
SST somatostatin
TFF3 trefoil factor 3 (intestinal)
TLR4 toll-like receptor 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAN versican
ZDHHC11 zinc finger, DHHC-type containing 11