BRD-K66792149_-666_A375_6.0_h_11.1_um Gene Set
Genes
51 genes differentially expressed following the BRD-K66792149_-666_A375_6.0_h_11.1_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
ADRB2
|
adrenoceptor beta 2, surface
|
|
ANK2
|
ankyrin 2, neuronal
|
|
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
|
ATF3
|
activating transcription factor 3
|
|
CD36
|
CD36 molecule (thrombospondin receptor)
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
|
CSTA
|
cystatin A (stefin A)
|
|
DDIT3
|
DNA-damage-inducible transcript 3
|
|
FHL2
|
four and a half LIM domains 2
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
|
GDF15
|
growth differentiation factor 15
|
|
GEM
|
GTP binding protein overexpressed in skeletal muscle
|
|
HMOX1
|
heme oxygenase 1
|
|
IGFBP3
|
insulin-like growth factor binding protein 3
|
|
JAG1
|
jagged 1
|
|
KRT14
|
keratin 14, type I
|
|
MDK
|
midkine (neurite growth-promoting factor 2)
|
|
MME
|
membrane metallo-endopeptidase
|
|
MT1G
|
metallothionein 1G
|
|
MT1H
|
metallothionein 1H
|
|
MT1HL1
|
metallothionein 1H-like 1
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
|
PDGFA
|
platelet-derived growth factor alpha polypeptide
|
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1
|
|
PMAIP1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
|
PPAP2B
|
phosphatidic acid phosphatase type 2B
|
|
PTN
|
pleiotrophin
|
|
SLC16A6
|
solute carrier family 16, member 6
|
|
SQSTM1
|
sequestosome 1
|
|
TP53
|
tumor protein p53
|
|
TRIB2
|
tribbles pseudokinase 2
|
|
TXNRD1
|
thioredoxin reductase 1
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
AGT
|
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
|
|
AURKA
|
aurora kinase A
|
|
CCNF
|
cyclin F
|
|
GALNT2
|
polypeptide N-acetylgalactosaminyltransferase 2
|
|
HPGD
|
hydroxyprostaglandin dehydrogenase 15-(NAD)
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
|
KPNA2
|
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
|
|
MBP
|
myelin basic protein
|
|
NPR3
|
natriuretic peptide receptor 3
|
|
NUP62
|
nucleoporin 62kDa
|
|
SAC3D1
|
SAC3 domain containing 1
|
|
SLC26A2
|
solute carrier family 26 (anion exchanger), member 2
|
|
SLC27A2
|
solute carrier family 27 (fatty acid transporter), member 2
|
|
SLC4A4
|
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
|
|
SLPI
|
secretory leukocyte peptidase inhibitor
|
|
TBC1D16
|
TBC1 domain family, member 16
|
|
TBC1D31
|
TBC1 domain family, member 31
|
