BRD-K66792149_-666_A375_6.0_h_11.1_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the BRD-K66792149_-666_A375_6.0_h_11.1_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANK2 ankyrin 2, neuronal
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CD36 CD36 molecule (thrombospondin receptor)
CHIC2 cysteine-rich hydrophobic domain 2
CSTA cystatin A (stefin A)
DDIT3 DNA-damage-inducible transcript 3
FHL2 four and a half LIM domains 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
JAG1 jagged 1
KRT14 keratin 14, type I
MDK midkine (neurite growth-promoting factor 2)
MME membrane metallo-endopeptidase
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDGFA platelet-derived growth factor alpha polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PTN pleiotrophin
SLC16A6 solute carrier family 16, member 6
SQSTM1 sequestosome 1
TP53 tumor protein p53
TRIB2 tribbles pseudokinase 2
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AURKA aurora kinase A
CCNF cyclin F
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
MBP myelin basic protein
NPR3 natriuretic peptide receptor 3
NUP62 nucleoporin 62kDa
SAC3D1 SAC3 domain containing 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLPI secretory leukocyte peptidase inhibitor
TBC1D16 TBC1 domain family, member 16
TBC1D31 TBC1 domain family, member 31