BRD-K66909449_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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37 genes differentially expressed following the BRD-K66909449_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CAST calpastatin
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
DDIT4 DNA-damage-inducible transcript 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GDF15 growth differentiation factor 15
GRB7 growth factor receptor-bound protein 7
HMGA1 high mobility group AT-hook 1
IQCG IQ motif containing G
LAMC2 laminin, gamma 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LY75 lymphocyte antigen 75
MMP12 matrix metallopeptidase 12
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PON2 paraoxonase 2
PTX3 pentraxin 3, long
RAI14 retinoic acid induced 14
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SPAG4 sperm associated antigen 4
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CLU clusterin
CORO1A coronin, actin binding protein, 1A
CRYAB crystallin, alpha B
CX3CR1 chemokine (C-X3-C motif) receptor 1
IFI6 interferon, alpha-inducible protein 6
KLK5 kallikrein-related peptidase 5
PCNA proliferating cell nuclear antigen
PCP4 Purkinje cell protein 4
RGS5 regulator of G-protein signaling 5
RTN2 reticulon 2
SNRPB small nuclear ribonucleoprotein polypeptides B and B1