| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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114 genes differentially expressed following the BRD-K67100011_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ANGPTL2 | angiopoietin-like 2 |
| ANXA1 | annexin A1 |
| CA2 | carbonic anhydrase II |
| CAPN2 | calpain 2, (m/II) large subunit |
| CD200 | CD200 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD9 | CD9 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHN1 | chimerin 1 |
| CLCA4 | chloride channel accessory 4 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL5A2 | collagen, type V, alpha 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CTBP2 | C-terminal binding protein 2 |
| CTSK | cathepsin K |
| CTSZ | cathepsin Z |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| DCN | decorin |
| DUOX2 | dual oxidase 2 |
| FBN2 | fibrillin 2 |
| GMPR | guanosine monophosphate reductase |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| HBD | hemoglobin, delta |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HMGN4 | high mobility group nucleosomal binding domain 4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KIAA1462 | KIAA1462 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAOA | monoamine oxidase A |
| MECOM | MDS1 and EVI1 complex locus |
| MME | membrane metallo-endopeptidase |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow |
| MYOF | myoferlin |
| NEB | nebulin |
| NOX4 | NADPH oxidase 4 |
| P3H2 | prolyl 3-hydroxylase 2 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAGE4 | P antigen family, member 4 (prostate associated) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PFKM | phosphofructokinase, muscle |
| PLBD1 | phospholipase B domain containing 1 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| POSTN | periostin, osteoblast specific factor |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCI | protein kinase C, iota |
| RCAN2 | regulator of calcineurin 2 |
| SULF1 | sulfatase 1 |
| SUSD4 | sushi domain containing 4 |
| TCF4 | transcription factor 4 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THY1 | Thy-1 cell surface antigen |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TPM2 | tropomyosin 2 (beta) |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM22 | tripartite motif containing 22 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TWIST1 | twist family bHLH transcription factor 1 |
| VCAN | versican |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| Symbol | Name |
|---|---|
| AFP | alpha-fetoprotein |
| APOC2 | apolipoprotein C-II |
| APOE | apolipoprotein E |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide |
| BEX1 | brain expressed, X-linked 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD164 | CD164 molecule, sialomucin |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHPT1 | choline phosphotransferase 1 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DSP | desmoplakin |
| EIF5 | eukaryotic translation initiation factor 5 |
| FABP7 | fatty acid binding protein 7, brain |
| GNAS | GNAS complex locus |
| HN1 | hematological and neurological expressed 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| KRT10 | keratin 10, type I |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MSX1 | msh homeobox 1 |
| MXRA7 | matrix-remodelling associated 7 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PKM | pyruvate kinase, muscle |
| PRDX1 | peroxiredoxin 1 |
| PRMT1 | protein arginine methyltransferase 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| QPRT | quinolinate phosphoribosyltransferase |
| RNASET2 | ribonuclease T2 |
| RNF167 | ring finger protein 167 |
| S100P | S100 calcium binding protein P |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| STX1A | syntaxin 1A (brain) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TUBB | tubulin, beta class I |
