BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_VCAP_6.0_h_10.0_um Gene Set
Genes
26 genes differentially expressed following the BRD-K67619794_2,6-difluoro-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
CDH3
|
cadherin 3, type 1, P-cadherin (placental)
|
|
IFI6
|
interferon, alpha-inducible protein 6
|
|
NPY
|
neuropeptide Y
|
|
PDLIM5
|
PDZ and LIM domain 5
|
|
PTGDS
|
prostaglandin D2 synthase 21kDa (brain)
|
|
RARRES1
|
retinoic acid receptor responder (tazarotene induced) 1
|
|
SLC16A3
|
solute carrier family 16 (monocarboxylate transporter), member 3
|
|
TMPRSS2
|
transmembrane protease, serine 2
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ACKR3
|
atypical chemokine receptor 3
|
|
ARL4C
|
ADP-ribosylation factor-like 4C
|
|
CPA3
|
carboxypeptidase A3 (mast cell)
|
|
CREB1
|
cAMP responsive element binding protein 1
|
|
DHCR7
|
7-dehydrocholesterol reductase
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
|
INSIG1
|
insulin induced gene 1
|
|
LDLR
|
low density lipoprotein receptor
|
|
LGALS8
|
lectin, galactoside-binding, soluble, 8
|
|
MMP2
|
matrix metallopeptidase 2
|
|
MSMO1
|
methylsterol monooxygenase 1
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
SQLE
|
squalene epoxidase
|
|
TNNT1
|
troponin T type 1 (skeletal, slow)
|
