BRD-K67808578_1391-0741_SKB_24.0_h_10.0_um Gene Set
Genes
50 genes differentially expressed following the BRD-K67808578_1391-0741_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
ALOX5
|
arachidonate 5-lipoxygenase
|
|
CDC25B
|
cell division cycle 25B
|
|
CTSL
|
cathepsin L
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
|
HLA-B
|
major histocompatibility complex, class I, B
|
|
IFI44L
|
interferon-induced protein 44-like
|
|
IFI6
|
interferon, alpha-inducible protein 6
|
|
KDM5D
|
lysine (K)-specific demethylase 5D
|
|
KLF2
|
Kruppel-like factor 2
|
|
LRP4
|
low density lipoprotein receptor-related protein 4
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
|
MMP1
|
matrix metallopeptidase 1
|
|
MMP7
|
matrix metallopeptidase 7
|
|
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1
|
|
NPY1R
|
neuropeptide Y receptor Y1
|
|
OAS1
|
2'-5'-oligoadenylate synthetase 1, 40/46kDa
|
|
OAS3
|
2'-5'-oligoadenylate synthetase 3, 100kDa
|
|
PNP
|
purine nucleoside phosphorylase
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
|
TGM2
|
transglutaminase 2
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TMEM176B
|
transmembrane protein 176B
|
|
TNFRSF10B
|
tumor necrosis factor receptor superfamily, member 10b
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ACSL4
|
acyl-CoA synthetase long-chain family member 4
|
|
ANXA3
|
annexin A3
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
|
AUTS2
|
autism susceptibility candidate 2
|
|
CADM1
|
cell adhesion molecule 1
|
|
CD24
|
CD24 molecule
|
|
CLC
|
Charcot-Leyden crystal galectin
|
|
EFEMP1
|
EGF containing fibulin-like extracellular matrix protein 1
|
|
ELANE
|
elastase, neutrophil expressed
|
|
ENC1
|
ectodermal-neural cortex 1 (with BTB domain)
|
|
HIST1H1C
|
histone cluster 1, H1c
|
|
HIST1H2BG
|
histone cluster 1, H2bg
|
|
KRT23
|
keratin 23, type I
|
|
MAGEA12
|
melanoma antigen family A12
|
|
MAGEA3
|
melanoma antigen family A3
|
|
MAGEA6
|
melanoma antigen family A6
|
|
NBEA
|
neurobeachin
|
|
NEDD4L
|
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
|
|
PDE10A
|
phosphodiesterase 10A
|
|
PON3
|
paraoxonase 3
|
|
PRG2
|
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
|
|
SCGB1D2
|
secretoglobin, family 1D, member 2
|
|
SERPINB3
|
serpin peptidase inhibitor, clade B (ovalbumin), member 3
|
|
SERPINB4
|
serpin peptidase inhibitor, clade B (ovalbumin), member 4
|
|
VTCN1
|
V-set domain containing T cell activation inhibitor 1
|
