| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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156 genes differentially expressed following the BRD-K67860401_GSK-3b Inhibitor VIII_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| ADAM9 | ADAM metallopeptidase domain 9 |
| APOC1 | apolipoprotein C-I |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BCL2L1 | BCL2-like 1 |
| BID | BH3 interacting domain death agonist |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CD163 | CD163 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLU | clusterin |
| COG7 | component of oligomeric golgi complex 7 |
| CORO1A | coronin, actin binding protein, 1A |
| CTSB | cathepsin B |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EXT1 | exostosin glycosyltransferase 1 |
| FAM60A | family with sequence similarity 60, member A |
| FCGBP | Fc fragment of IgG binding protein |
| GDF15 | growth differentiation factor 15 |
| GPNMB | glycoprotein (transmembrane) nmb |
| HBD | hemoglobin, delta |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BK | histone cluster 1, H2bk |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL1RN | interleukin 1 receptor antagonist |
| IPO13 | importin 13 |
| ISOC1 | isochorismatase domain containing 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JAG1 | jagged 1 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LYZ | lysozyme |
| MMP9 | matrix metallopeptidase 9 |
| MSMB | microseminoprotein, beta- |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NVL | nuclear VCP-like |
| OPN3 | opsin 3 |
| PALLD | palladin, cytoskeletal associated protein |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PMM2 | phosphomannomutase 2 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PPL | periplakin |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| S100A8 | S100 calcium binding protein A8 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRGN | serglycin |
| STAB1 | stabilin 1 |
| TARP | TCR gamma alternate reading frame protein |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRD | T cell receptor delta locus |
| ZNF274 | zinc finger protein 274 |
| Symbol | Name |
|---|---|
| AK1 | adenylate kinase 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| ARL4A | ADP-ribosylation factor-like 4A |
| ASPH | aspartate beta-hydroxylase |
| BAG2 | BCL2-associated athanogene 2 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CDC42 | cell division cycle 42 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHMP1B | charged multivesicular body protein 1B |
| CHMP6 | charged multivesicular body protein 6 |
| CHRDL1 | chordin-like 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CKAP4 | cytoskeleton-associated protein 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EGR3 | early growth response 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EIF5A | eukaryotic translation initiation factor 5A |
| FBLN1 | fibulin 1 |
| FBN1 | fibrillin 1 |
| FBXO9 | F-box protein 9 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| G0S2 | G0/G1 switch 2 |
| GAS1 | growth arrest-specific 1 |
| GPC3 | glypican 3 |
| GPM6B | glycoprotein M6B |
| HDAC6 | histone deacetylase 6 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| ITGA6 | integrin, alpha 6 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| MFAP2 | microfibrillar-associated protein 2 |
| MGP | matrix Gla protein |
| MIA | melanoma inhibitory activity |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NEBL | nebulette |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PIP | prolactin-induced protein |
| PLEC | plectin |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) |
| RPL27A | ribosomal protein L27a |
| RPS11 | ribosomal protein S11 |
| S100A2 | S100 calcium binding protein A2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SFRP1 | secreted frizzled-related protein 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SULF1 | sulfatase 1 |
| SYNM | synemin, intermediate filament protein |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM5 | transmembrane protein 5 |
| TPBG | trophoblast glycoprotein |
| TSPAN13 | tetraspanin 13 |
| TSPAN8 | tetraspanin 8 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
