Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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113 genes differentially expressed following the BRD-K67860401_GSK-3b Inhibitor VIII_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACKR3 | atypical chemokine receptor 3 |
AEBP1 | AE binding protein 1 |
ANGPT1 | angiopoietin 1 |
ANXA10 | annexin A10 |
APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
AREG | amphiregulin |
ARHGAP29 | Rho GTPase activating protein 29 |
ASPN | asporin |
ATF3 | activating transcription factor 3 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CCL4 | chemokine (C-C motif) ligand 4 |
CCL8 | chemokine (C-C motif) ligand 8 |
CCND2 | cyclin D2 |
CD52 | CD52 molecule |
CD83 | CD83 molecule |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CLDN7 | claudin 7 |
COL5A2 | collagen, type V, alpha 2 |
CPE | carboxypeptidase E |
CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
DPT | dermatopontin |
EGFL6 | EGF-like-domain, multiple 6 |
EMP1 | epithelial membrane protein 1 |
EPCAM | epithelial cell adhesion molecule |
FAM171A1 | family with sequence similarity 171, member A1 |
FBLN1 | fibulin 1 |
FN1 | fibronectin 1 |
G0S2 | G0/G1 switch 2 |
GLUL | glutamate-ammonia ligase |
GPNMB | glycoprotein (transmembrane) nmb |
GRHL2 | grainyhead-like 2 (Drosophila) |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IDO1 | indoleamine 2,3-dioxygenase 1 |
ITM2A | integral membrane protein 2A |
KRT19 | keratin 19, type I |
LY6E | lymphocyte antigen 6 complex, locus E |
MECOM | MDS1 and EVI1 complex locus |
MMP9 | matrix metallopeptidase 9 |
MT1M | metallothionein 1M |
NELL2 | NEL-like 2 (chicken) |
NPR3 | natriuretic peptide receptor 3 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
PCP4 | Purkinje cell protein 4 |
PDE9A | phosphodiesterase 9A |
PEG3 | paternally expressed 3 |
RAB25 | RAB25, member RAS oncogene family |
RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
RBP1 | retinol binding protein 1, cellular |
RBP4 | retinol binding protein 4, plasma |
RGS1 | regulator of G-protein signaling 1 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SORBS2 | sorbin and SH3 domain containing 2 |
SPARCL1 | SPARC-like 1 (hevin) |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMEM30B | transmembrane protein 30B |
TPD52L1 | tumor protein D52-like 1 |
TRD | T cell receptor delta locus |
TRDV3 | T cell receptor delta variable 3 |
TXNIP | thioredoxin interacting protein |
VNN1 | vanin 1 |
Symbol | Name |
---|---|
AGRN | agrin |
AK4 | adenylate kinase 4 |
AZU1 | azurocidin 1 |
C6ORF62 | chromosome 6 open reading frame 62 |
CALR | calreticulin |
CANX | calnexin |
CDCA4 | cell division cycle associated 4 |
CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
CHN1 | chimerin 1 |
DHCR24 | 24-dehydrocholesterol reductase |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
EIF3K | eukaryotic translation initiation factor 3, subunit K |
EIF5 | eukaryotic translation initiation factor 5 |
ELANE | elastase, neutrophil expressed |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GLS | glutaminase |
HSPA2 | heat shock 70kDa protein 2 |
INSIG1 | insulin induced gene 1 |
KIF14 | kinesin family member 14 |
LYPLA1 | lysophospholipase I |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MBNL2 | muscleblind-like splicing regulator 2 |
MFSD10 | major facilitator superfamily domain containing 10 |
NREP | neuronal regeneration related protein |
OXA1L | oxidase (cytochrome c) assembly 1-like |
OXTR | oxytocin receptor |
PDGFD | platelet derived growth factor D |
PLAT | plasminogen activator, tissue |
PON2 | paraoxonase 2 |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
PRKCA | protein kinase C, alpha |
RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
STXBP2 | syntaxin binding protein 2 |
TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEM45A | transmembrane protein 45A |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
TNS3 | tensin 3 |
UBE3C | ubiquitin protein ligase E3C |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |