BRD-K67868012_PI 103 hydrochloride_MCF7_24.0_h_11.1_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K67868012_PI 103 hydrochloride_MCF7_24.0_h_11.1_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BMP2 bone morphogenetic protein 2
CD24 CD24 molecule
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
F2RL1 coagulation factor II (thrombin) receptor-like 1
GSN gelsolin
HSPA2 heat shock 70kDa protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JAG1 jagged 1
KRT15 keratin 15, type I
MUC2 mucin 2, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NAP1L1 nucleosome assembly protein 1-like 1
NEB nebulin
NLRP2 NLR family, pyrin domain containing 2
OLFM4 olfactomedin 4
P3H2 prolyl 3-hydroxylase 2
PLCB4 phospholipase C, beta 4
RRAD Ras-related associated with diabetes
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TKTL1 transketolase-like 1

decreased expression

Symbol Name
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
CRABP2 cellular retinoic acid binding protein 2
GOLT1B golgi transport 1B
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KYNU kynureninase
LAGE3 L antigen family, member 3
LMO2 LIM domain only 2 (rhombotin-like 1)
MAP7 microtubule-associated protein 7
PLK1 polo-like kinase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PTTG1 pituitary tumor-transforming 1
RAD21 RAD21 homolog (S. pombe)
RGS4 regulator of G-protein signaling 4
TPM4 tropomyosin 4
UBE2S ubiquitin-conjugating enzyme E2S
VAT1 vesicle amine transport 1
VCAN versican
Funding