BRD-K67868012_PI-103_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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68 genes differentially expressed following the BRD-K67868012_PI-103_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCAS3 breast carcinoma amplified sequence 3
CA12 carbonic anhydrase XII
CCNG1 cyclin G1
CD59 CD59 molecule, complement regulatory protein
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPS8 epidermal growth factor receptor pathway substrate 8
FAM13A family with sequence similarity 13, member A
FAR2 fatty acyl CoA reductase 2
FBP1 fructose-1,6-bisphosphatase 1
GALC galactosylceramidase
HOXC6 homeobox C6
IGFBP1 insulin-like growth factor binding protein 1
KDM3A lysine (K)-specific demethylase 3A
LARS leucyl-tRNA synthetase
LGALS4 lectin, galactoside-binding, soluble, 4
MGP matrix Gla protein
MKRN1 makorin ring finger protein 1
NEFL neurofilament, light polypeptide
NOTCH2NL notch 2 N-terminal like
NPDC1 neural proliferation, differentiation and control, 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTS neurotensin
PCCB propionyl CoA carboxylase, beta polypeptide
PLBD1 phospholipase B domain containing 1
PNMA2 paraneoplastic Ma antigen 2
PROM1 prominin 1
PTHLH parathyroid hormone-like hormone
RBM47 RNA binding motif protein 47
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TBX2 T-box 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
BTG3 BTG family, member 3
CDC25A cell division cycle 25A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKB creatine kinase, brain
DDIT4 DNA-damage-inducible transcript 4
EMP1 epithelial membrane protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
KLK10 kallikrein-related peptidase 10
KRT4 keratin 4, type II
KRT5 keratin 5, type II
MAT2A methionine adenosyltransferase II, alpha
MMP11 matrix metallopeptidase 11
NXN nucleoredoxin
PCP4 Purkinje cell protein 4
PEG10 paternally expressed 10
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RGCC regulator of cell cycle
S100A2 S100 calcium binding protein A2
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3
TPPP3 tubulin polymerization-promoting protein family member 3
TPSB2 tryptase beta 2 (gene/pseudogene)
ZFP36L1 ZFP36 ring finger protein-like 1