BRD-K67870070_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-K67870070_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
AHNAK AHNAK nucleoprotein
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ANXA1 annexin A1
ANXA3 annexin A3
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
AXL AXL receptor tyrosine kinase
BMP4 bone morphogenetic protein 4
C1ORF116 chromosome 1 open reading frame 116
CAPN2 calpain 2, (m/II) large subunit
CAV2 caveolin 2
CD52 CD52 molecule
CFD complement factor D (adipsin)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLC Charcot-Leyden crystal galectin
CSRP1 cysteine and glycine-rich protein 1
CYBB cytochrome b-245, beta polypeptide
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DRAM1 DNA-damage regulated autophagy modulator 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GBP1 guanylate binding protein 1, interferon-inducible
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBB hemoglobin, beta
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JAG1 jagged 1
JUN jun proto-oncogene
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT7 keratin 7, type II
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICALL1 MICAL-like 1
MME membrane metallo-endopeptidase
MMP7 matrix metallopeptidase 7
MT2A metallothionein 2A
OXSR1 oxidative stress responsive 1
PALLD palladin, cytoskeletal associated protein
PAWR PRKC, apoptosis, WT1, regulator
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RGS2 regulator of G-protein signaling 2
RIPK4 receptor-interacting serine-threonine kinase 4
SAMD4A sterile alpha motif domain containing 4A
SLC43A3 solute carrier family 43, member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD3 SMAD family member 3
SYNM synemin, intermediate filament protein
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGFB2 transforming growth factor, beta 2
TM4SF1 transmembrane 4 L six family member 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TPM1 tropomyosin 1 (alpha)
TUBB2A tubulin, beta 2A class IIa
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CD200 CD200 molecule
CNPY3 canopy FGF signaling regulator 3
COL15A1 collagen, type XV, alpha 1
COL5A2 collagen, type V, alpha 2
DDIT4 DNA-damage-inducible transcript 4
DHRS7 dehydrogenase/reductase (SDR family) member 7
ETV1 ets variant 1
FBLN1 fibulin 1
GPM6B glycoprotein M6B
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IGHM immunoglobulin heavy constant mu
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SOX2 SRY (sex determining region Y)-box 2
STAG2 stromal antigen 2
TCF4 transcription factor 4
TOR1AIP1 torsin A interacting protein 1
ZFP36L2 ZFP36 ring finger protein-like 2