BRD-K68038686_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K68038686_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CRELD2 cysteine-rich with EGF-like domains 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
FAM69A family with sequence similarity 69, member A
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
LOC100505650 uncharacterized LOC100505650
MAP7 microtubule-associated protein 7
MMP7 matrix metallopeptidase 7
MPO myeloperoxidase
MSMB microseminoprotein, beta-
NNMT nicotinamide N-methyltransferase
PDIA3 protein disulfide isomerase family A, member 3
PDZK1IP1 PDZK1 interacting protein 1
PPIB peptidylprolyl isomerase B (cyclophilin B)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
S100P S100 calcium binding protein P
SCGB2A2 secretoglobin, family 2A, member 2
SDF2L1 stromal cell-derived factor 2-like 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SSR1 signal sequence receptor, alpha
XBP1 X-box binding protein 1

decreased expression

Symbol Name
EREG epiregulin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
NRIP1 nuclear receptor interacting protein 1
SRPX sushi-repeat containing protein, X-linked
TMEM164 transmembrane protein 164