| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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175 genes differentially expressed following the BRD-K68174511_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 |
| ADCK3 | aarF domain containing kinase 3 |
| ADM | adrenomedullin |
| AFF1 | AF4/FMR2 family, member 1 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| ANKRD10 | ankyrin repeat domain 10 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASXL1 | additional sex combs like transcriptional regulator 1 |
| ATF4 | activating transcription factor 4 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BICC1 | BicC family RNA binding protein 1 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CAPN3 | calpain 3, (p94) |
| CCNG2 | cyclin G2 |
| CCNL1 | cyclin L1 |
| CLK4 | CDC-like kinase 4 |
| CRISP3 | cysteine-rich secretory protein 3 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 |
| DENND5A | DENN/MADD domain containing 5A |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DUSP1 | dual specificity phosphatase 1 |
| FAM129A | family with sequence similarity 129, member A |
| FNBP4 | formin binding protein 4 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| HAL | histidine ammonia-lyase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL6ST | interleukin 6 signal transducer |
| IRS2 | insulin receptor substrate 2 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIF20A | kinesin family member 20A |
| LDLR | low density lipoprotein receptor |
| LOC399491 | |
| LOX | lysyl oxidase |
| LYST | lysosomal trafficking regulator |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALT1 | MALT1 paracaspase |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MED1 | mediator complex subunit 1 |
| MTA1 | metastasis associated 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MXI1 | MAX interactor 1, dimerization protein |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NOTCH2NL | notch 2 N-terminal like |
| NPC1 | Niemann-Pick disease, type C1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRAF2 | PRA1 domain family, member 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM39 | RNA binding motif protein 39 |
| RBM5 | RNA binding motif protein 5 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SYNJ2 | synaptojanin 2 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCERG1 | transcription elongation regulator 1 |
| TKTL1 | transketolase-like 1 |
| UBAP2 | ubiquitin associated protein 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| WAC | WW domain containing adaptor with coiled-coil |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADIRF | adipogenesis regulatory factor |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| ATP5H | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d |
| AUTS2 | autism susceptibility candidate 2 |
| B3GNT1 | |
| C1QB | complement component 1, q subcomponent, B chain |
| CADM1 | cell adhesion molecule 1 |
| CCND3 | cyclin D3 |
| CDC25A | cell division cycle 25A |
| CFD | complement factor D (adipsin) |
| CKB | creatine kinase, brain |
| CLEC3B | C-type lectin domain family 3, member B |
| COL6A2 | collagen, type VI, alpha 2 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DUSP22 | dual specificity phosphatase 22 |
| EMP2 | epithelial membrane protein 2 |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GRB2 | growth factor receptor-bound protein 2 |
| GSTA1 | glutathione S-transferase alpha 1 |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HBB | hemoglobin, beta |
| HN1 | hematological and neurological expressed 1 |
| ICT1 | immature colon carcinoma transcript 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGKV1-5 | immunoglobulin kappa variable 1-5 |
| IGL | immunoglobulin lambda locus |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ISOC1 | isochorismatase domain containing 1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KRT19 | keratin 19, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LRRC17 | leucine rich repeat containing 17 |
| MAOA | monoamine oxidase A |
| MEIS2 | Meis homeobox 2 |
| MGP | matrix Gla protein |
| MID1 | midline 1 |
| MMP10 | matrix metallopeptidase 10 |
| MRPL11 | mitochondrial ribosomal protein L11 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPS7 | mitochondrial ribosomal protein S7 |
| MXRA7 | matrix-remodelling associated 7 |
| MYL9 | myosin, light chain 9, regulatory |
| NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 |
| NELL2 | NEL-like 2 (chicken) |
| OLFM4 | olfactomedin 4 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCP4 | Purkinje cell protein 4 |
| PEG3 | paternally expressed 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| POU2AF1 | POU class 2 associating factor 1 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTN | pleiotrophin |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| REG1A | regenerating islet-derived 1 alpha |
| REG3A | regenerating islet-derived 3 alpha |
| RGCC | regulator of cell cycle |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| S100A8 | S100 calcium binding protein A8 |
| SDC2 | syndecan 2 |
| SDC4 | syndecan 4 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEPT9 | septin 9 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SPON1 | spondin 1, extracellular matrix protein |
| SST | somatostatin |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUMO2 | small ubiquitin-like modifier 2 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
| TK1 | thymidine kinase 1, soluble |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM50B | transmembrane protein 50B |
| TMSB15B | thymosin beta 15B |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIM2 | tripartite motif containing 2 |
| TUSC3 | tumor suppressor candidate 3 |
