| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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149 genes differentially expressed following the BRD-K68174511_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANXA4 | annexin A4 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BRD8 | bromodomain containing 8 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCNG2 | cyclin G2 |
| CENPE | centromere protein E, 312kDa |
| CLEC2B | C-type lectin domain family 2, member B |
| COL9A3 | collagen, type IX, alpha 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM50A | family with sequence similarity 50, member A |
| GCC2 | GRIP and coiled-coil domain containing 2 |
| GDF15 | growth differentiation factor 15 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GSDMB | gasdermin B |
| GUSB | glucuronidase, beta |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPA1A | heat shock 70kDa protein 1A |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IRF7 | interferon regulatory factor 7 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIAA1033 | KIAA1033 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LUM | lumican |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPT | microtubule-associated protein tau |
| MGLL | monoglyceride lipase |
| MVP | major vault protein |
| MX2 | MX dynamin-like GTPase 2 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NNMT | nicotinamide N-methyltransferase |
| NUDCD3 | NudC domain containing 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PIH1D1 | PIH1 domain containing 1 |
| PLIN2 | perilipin 2 |
| RAP1GAP | RAP1 GTPase activating protein |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBM39 | RNA binding motif protein 39 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS1 | regulator of G-protein signaling 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| AIM1 | absent in melanoma 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ASF1A | anti-silencing function 1A histone chaperone |
| B3GNT1 | |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CBFB | core-binding factor, beta subunit |
| CCDC85B | coiled-coil domain containing 85B |
| CDC25A | cell division cycle 25A |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CNN3 | calponin 3, acidic |
| COTL1 | coactosin-like F-actin binding protein 1 |
| CPE | carboxypeptidase E |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP14 | dual specificity phosphatase 14 |
| DUT | deoxyuridine triphosphatase |
| EFNB2 | ephrin-B2 |
| EIF4E | eukaryotic translation initiation factor 4E |
| ENO1 | enolase 1, (alpha) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEN1 | flap structure-specific endonuclease 1 |
| GATA3 | GATA binding protein 3 |
| GLRX5 | glutaredoxin 5 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HBB | hemoglobin, beta |
| HES1 | hes family bHLH transcription factor 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| LOXL1 | lysyl oxidase-like 1 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAT2A | methionine adenosyltransferase II, alpha |
| MDFIC | MyoD family inhibitor domain containing |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MYCBP | MYC binding protein |
| NELL2 | NEL-like 2 (chicken) |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| OLFM4 | olfactomedin 4 |
| PALLD | palladin, cytoskeletal associated protein |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCH | protein kinase C, eta |
| PRR7 | proline rich 7 (synaptic) |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| REG3A | regenerating islet-derived 3 alpha |
| RPIA | ribose 5-phosphate isomerase A |
| RRP1B | ribosomal RNA processing 1B |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SDC2 | syndecan 2 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLIRP | SRA stem-loop interacting RNA binding protein |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
| SRM | spermidine synthase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SYNGR1 | synaptogyrin 1 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TMEM109 | transmembrane protein 109 |
| TMX1 | thioredoxin-related transmembrane protein 1 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| UBE2N | ubiquitin-conjugating enzyme E2N |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| URI1 | URI1, prefoldin-like chaperone |
