| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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253 genes differentially expressed following the BRD-K68174511_torin-2_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ABHD4 | abhydrolase domain containing 4 |
| ADCY1 | adenylate cyclase 1 (brain) |
| AK5 | adenylate kinase 5 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF4 | activating transcription factor 4 |
| BPI | bactericidal/permeability-increasing protein |
| BPTF | bromodomain PHD finger transcription factor |
| BRD8 | bromodomain containing 8 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CAMLG | calcium modulating ligand |
| CAPN3 | calpain 3, (p94) |
| CAPRIN2 | caprin family member 2 |
| CCDC28A | coiled-coil domain containing 28A |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CCNL1 | cyclin L1 |
| CD44 | CD44 molecule (Indian blood group) |
| CDK19 | cyclin-dependent kinase 19 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLC | Charcot-Leyden crystal galectin |
| CLEC2B | C-type lectin domain family 2, member B |
| COCH | cochlin |
| CRISP3 | cysteine-rich secretory protein 3 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide |
| CTSK | cathepsin K |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FNTA | farnesyltransferase, CAAX box, alpha |
| FOXO4 | forkhead box O4 |
| FRZB | frizzled-related protein |
| G0S2 | G0/G1 switch 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GDF15 | growth differentiation factor 15 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPATCH8 | G patch domain containing 8 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GPX4 | glutathione peroxidase 4 |
| GUSB | glucuronidase, beta |
| HDAC6 | histone deacetylase 6 |
| HEBP2 | heme binding protein 2 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST3H2A | histone cluster 3, H2a |
| HMGA1 | high mobility group AT-hook 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IFRD1 | interferon-related developmental regulator 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KDSR | 3-ketodihydrosphingosine reductase |
| KIAA0907 | KIAA0907 |
| KYNU | kynureninase |
| LETMD1 | LETM1 domain containing 1 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LOC399491 | |
| MCOLN1 | mucolipin 1 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 |
| MMP9 | matrix metallopeptidase 9 |
| MXRA7 | matrix-remodelling associated 7 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPC1 | Niemann-Pick disease, type C1 |
| NPY | neuropeptide Y |
| NSUN5 | NOP2/Sun domain family, member 5 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NSUN5P2 | NOP2/Sun domain family, member 5 pseudogene 2 |
| OSBPL1A | oxysterol binding protein-like 1A |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PGLS | 6-phosphogluconolactonase |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 |
| PLSCR1 | phospholipid scramblase 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNKP | polynucleotide kinase 3'-phosphatase |
| RIOK3 | RIO kinase 3 |
| RPL36 | ribosomal protein L36 |
| RSRP1 | arginine/serine-rich protein 1 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SESN1 | sestrin 1 |
| SGSM2 | small G protein signaling modulator 2 |
| SLC35E2B | solute carrier family 35, member E2B |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SQSTM1 | sequestosome 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STX1A | syntaxin 1A (brain) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TBC1D15 | TBC1 domain family, member 15 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TPP1 | tripeptidyl peptidase I |
| UBXN1 | UBX domain protein 1 |
| VAT1 | vesicle amine transport 1 |
| WDR19 | WD repeat domain 19 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACOT9 | acyl-CoA thioesterase 9 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AK4 | adenylate kinase 4 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AUTS2 | autism susceptibility candidate 2 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| BMPR1A | bone morphogenetic protein receptor, type IA |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CA12 | carbonic anhydrase XII |
| CADM1 | cell adhesion molecule 1 |
| CALR | calreticulin |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCND2 | cyclin D2 |
| CD47 | CD47 molecule |
| CD58 | CD58 molecule |
| CDC42 | cell division cycle 42 |
| CKAP4 | cytoskeleton-associated protein 4 |
| CLU | clusterin |
| COL5A1 | collagen, type V, alpha 1 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) |
| CTSC | cathepsin C |
| CTSZ | cathepsin Z |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYB5A | cytochrome b5 type A (microsomal) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEFB1 | defensin, beta 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EGF | epidermal growth factor |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EMP2 | epithelial membrane protein 2 |
| ENO1 | enolase 1, (alpha) |
| EPHB2 | EPH receptor B2 |
| FAM98A | family with sequence similarity 98, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FNDC3B | fibronectin type III domain containing 3B |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPX2 | glutathione peroxidase 2 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HK2 | hexokinase 2 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPB8 | heat shock 22kDa protein 8 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| IL32 | interleukin 32 |
| INSIG1 | insulin induced gene 1 |
| ITM2C | integral membrane protein 2C |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KAZN | kazrin, periplakin interacting protein |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
| KRT13 | keratin 13, type I |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LOXL1 | lysyl oxidase-like 1 |
| MAL | mal, T-cell differentiation protein |
| MATN2 | matrilin 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MMP10 | matrix metallopeptidase 10 |
| MPZL2 | myelin protein zero-like 2 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTSS1 | metastasis suppressor 1 |
| MYCBP | MYC binding protein |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NCAM1 | neural cell adhesion molecule 1 |
| NEBL | nebulette |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOTCH2 | notch 2 |
| NRCAM | neuronal cell adhesion molecule |
| NREP | neuronal regeneration related protein |
| OLFML3 | olfactomedin-like 3 |
| P3H2 | prolyl 3-hydroxylase 2 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PALLD | palladin, cytoskeletal associated protein |
| PAX8 | paired box 8 |
| PCP4 | Purkinje cell protein 4 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PFN2 | profilin 2 |
| PGK1 | phosphoglycerate kinase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIR | pirin (iron-binding nuclear protein) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRDX2 | peroxiredoxin 2 |
| PRDX4 | peroxiredoxin 4 |
| QPRT | quinolinate phosphoribosyltransferase |
| RIN2 | Ras and Rab interactor 2 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RRAD | Ras-related associated with diabetes |
| RRBP1 | ribosome binding protein 1 |
| RSU1 | Ras suppressor protein 1 |
| SCARB1 | scavenger receptor class B, member 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDC1 | syndecan 1 |
| SDC2 | syndecan 2 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SORD | sorbitol dehydrogenase |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SQLE | squalene epoxidase |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCF4 | transcription factor 4 |
| TFRC | transferrin receptor |
| THBS1 | thrombospondin 1 |
| TNC | tenascin C |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM16 | tripartite motif containing 16 |
| TRIM2 | tripartite motif containing 2 |
| UCK2 | uridine-cytidine kinase 2 |
| UXS1 | UDP-glucuronate decarboxylase 1 |
| VCAM1 | vascular cell adhesion molecule 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
