| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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84 genes differentially expressed following the BRD-K68174511_torin-2_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APOD | apolipoprotein D |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COBL | cordon-bleu WH2 repeat protein |
| CPM | carboxypeptidase M |
| CYTH1 | cytohesin 1 |
| DEFB1 | defensin, beta 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| GPX3 | glutathione peroxidase 3 |
| HOXC6 | homeobox C6 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IRS1 | insulin receptor substrate 1 |
| IRS2 | insulin receptor substrate 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KIF14 | kinesin family member 14 |
| KRT15 | keratin 15, type I |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAOA | monoamine oxidase A |
| METTL7A | methyltransferase like 7A |
| MGP | matrix Gla protein |
| MTSS1 | metastasis suppressor 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTN1 | actinin, alpha 1 |
| AK4 | adenylate kinase 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CCND1 | cyclin D1 |
| CDC25A | cell division cycle 25A |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| COL4A5 | collagen, type IV, alpha 5 |
| DACH1 | dachshund family transcription factor 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EDNRA | endothelin receptor type A |
| EGR2 | early growth response 2 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked |
| ELANE | elastase, neutrophil expressed |
| EREG | epiregulin |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GPI | glucose-6-phosphate isomerase |
| GPX2 | glutathione peroxidase 2 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL1B | interleukin 1, beta |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRRC59 | leucine rich repeat containing 59 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MPO | myeloperoxidase |
| NID1 | nidogen 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PON2 | paraoxonase 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RPIA | ribose 5-phosphate isomerase A |
| S100P | S100 calcium binding protein P |
| SCG5 | secretogranin V |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SELENBP1 | selenium binding protein 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR1A | small proline-rich protein 1A |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFRC | transferrin receptor |
| XIST | X inactive specific transcript (non-protein coding) |
