| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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134 genes differentially expressed following the BRD-K68174511_torin-2_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BRD8 | bromodomain containing 8 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFH | complement factor H |
| CGA | glycoprotein hormones, alpha polypeptide |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DCN | decorin |
| EFNA1 | ephrin-A1 |
| FNTA | farnesyltransferase, CAAX box, alpha |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GPX3 | glutathione peroxidase 3 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| HBP1 | HMG-box transcription factor 1 |
| HMGB2 | high mobility group box 2 |
| HOXC6 | homeobox C6 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ITM2A | integral membrane protein 2A |
| KIAA0907 | KIAA0907 |
| KIF14 | kinesin family member 14 |
| KLHL21 | kelch-like family member 21 |
| KLHL24 | kelch-like family member 24 |
| LOC100272216 | uncharacterized LOC100272216 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| METTL7A | methyltransferase like 7A |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PNKP | polynucleotide kinase 3'-phosphatase |
| PSPC1 | paraspeckle component 1 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RIOK3 | RIO kinase 3 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STX1A | syntaxin 1A (brain) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| Symbol | Name |
|---|---|
| ACTN1 | actinin, alpha 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| CCND1 | cyclin D1 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHEK1 | checkpoint kinase 1 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRCT1 | cysteine-rich C-terminal 1 |
| CSTA | cystatin A (stefin A) |
| CTSC | cathepsin C |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKC1 | dyskeratosis congenita 1, dyskerin |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EREG | epiregulin |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL2 | four and a half LIM domains 2 |
| FOSL1 | FOS-like antigen 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GNAS | GNAS complex locus |
| GSTP1 | glutathione S-transferase pi 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HES1 | hes family bHLH transcription factor 1 |
| HK2 | hexokinase 2 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSPA1A | heat shock 70kDa protein 1A |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| ISOC1 | isochorismatase domain containing 1 |
| KRT14 | keratin 14, type I |
| KRT5 | keratin 5, type II |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa |
| PON2 | paraoxonase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTHLH | parathyroid hormone-like hormone |
| RPIA | ribose 5-phosphate isomerase A |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A8 | S100 calcium binding protein A8 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SFN | stratifin |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SPRR2B | small proline-rich protein 2B |
| SPRR3 | small proline-rich protein 3 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| THAP11 | THAP domain containing 11 |
| THBS1 | thrombospondin 1 |
| WT1 | Wilms tumor 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
