BRD-K68246049_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K68246049_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
COPA coatomer protein complex, subunit alpha
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EZR ezrin
FABP4 fatty acid binding protein 4, adipocyte
FNDC3B fibronectin type III domain containing 3B
FOXO3 forkhead box O3
GPM6B glycoprotein M6B
HOXA5 homeobox A5
HOXB2 homeobox B2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
IGFBP3 insulin-like growth factor binding protein 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KAZN kazrin, periplakin interacting protein
LAMB1 laminin, beta 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MCL1 myeloid cell leukemia 1
NDRG1 N-myc downstream regulated 1
NRIP1 nuclear receptor interacting protein 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAP1GAP RAP1 GTPase activating protein
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RND3 Rho family GTPase 3
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SIK1 salt-inducible kinase 1
SKAP2 src kinase associated phosphoprotein 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMAD3 SMAD family member 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPD52 tumor protein D52
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
VCAN versican

decreased expression

Symbol Name
CCND1 cyclin D1
CEMIP cell migration inducing protein, hyaluronan binding
CFB complement factor B
GREB1 growth regulation by estrogen in breast cancer 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP1 insulin-like growth factor binding protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LCN2 lipocalin 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MT1E metallothionein 1E
MT1X metallothionein 1X
PCDH9 protocadherin 9
PCP4 Purkinje cell protein 4
RAD51C RAD51 paralog C
SC5D sterol-C5-desaturase
SQRDL sulfide quinone reductase-like (yeast)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5