Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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54 genes differentially expressed following the BRD-K68313733_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
ABHD4 | abhydrolase domain containing 4 |
AKR1C1 | aldo-keto reductase family 1, member C1 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
COL6A2 | collagen, type VI, alpha 2 |
CXCL6 | chemokine (C-X-C motif) ligand 6 |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
EIF5A | eukaryotic translation initiation factor 5A |
FOSL1 | FOS-like antigen 1 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
GLUL | glutamate-ammonia ligase |
GPX2 | glutathione peroxidase 2 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
OLFM4 | olfactomedin 4 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SOWAHC | sosondowah ankyrin repeat domain family member C |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
TFF3 | trefoil factor 3 (intestinal) |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TNPO1 | transportin 1 |
TUBB2A | tubulin, beta 2A class IIa |
TXNRD1 | thioredoxin reductase 1 |
Symbol | Name |
---|---|
AGR2 | anterior gradient 2 |
BAMBI | BMP and activin membrane-bound inhibitor |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CRISP3 | cysteine-rich secretory protein 3 |
DEPTOR | DEP domain containing MTOR-interacting protein |
IFI44L | interferon-induced protein 44-like |
IFITM1 | interferon induced transmembrane protein 1 |
IGFBP7 | insulin-like growth factor binding protein 7 |
LEF1 | lymphoid enhancer-binding factor 1 |
LEPR | leptin receptor |
LRRC17 | leucine rich repeat containing 17 |
LXN | latexin |
PLIN1 | perilipin 1 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SERINC5 | serine incorporator 5 |
SFRP4 | secreted frizzled-related protein 4 |
SLPI | secretory leukocyte peptidase inhibitor |
SRPX | sushi-repeat containing protein, X-linked |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TRIM22 | tripartite motif containing 22 |
TSC22D3 | TSC22 domain family, member 3 |
XBP1 | X-box binding protein 1 |