| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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152 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_CL34_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ATXN1 | ataxin 1 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| CALD1 | caldesmon 1 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CES1 | carboxylesterase 1 |
| CLU | clusterin |
| COL5A2 | collagen, type V, alpha 2 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAPK1 | death-associated protein kinase 1 |
| DEFB1 | defensin, beta 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EFHD1 | EF-hand domain family, member D1 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EZR | ezrin |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOLR1 | folate receptor 1 (adult) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GLRX | glutaredoxin (thioltransferase) |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HAMP | hepcidin antimicrobial peptide |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL1R1 | interleukin 1 receptor, type I |
| IL6ST | interleukin 6 signal transducer |
| ITM2A | integral membrane protein 2A |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LPIN2 | lipin 2 |
| MAGEA3 | melanoma antigen family A3 |
| MAL | mal, T-cell differentiation protein |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MGP | matrix Gla protein |
| NNMT | nicotinamide N-methyltransferase |
| NRN1 | neuritin 1 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDZK1 | PDZ domain containing 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEG3 | paternally expressed 3 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| RBP4 | retinol binding protein 4, plasma |
| SEPT6 | septin 6 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH2D1A | SH2 domain containing 1A |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SST | somatostatin |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| TDO2 | tryptophan 2,3-dioxygenase |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFB1 | transforming growth factor, beta 1 |
| THBS1 | thrombospondin 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSPYL5 | TSPY-like 5 |
| TXNIP | thioredoxin interacting protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WIF1 | WNT inhibitory factor 1 |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| ADORA2B | adenosine A2b receptor |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP5D | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit |
| BOP1 | block of proliferation 1 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CANT1 | calcium activated nucleotidase 1 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CCNB2 | cyclin B2 |
| CD320 | CD320 molecule |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLTB | clathrin, light chain B |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYC1 | cytochrome c-1 |
| CYCS | cytochrome c, somatic |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DLD | dihydrolipoamide dehydrogenase |
| DUOX2 | dual oxidase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ENOPH1 | enolase-phosphatase 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GPA33 | glycoprotein A33 (transmembrane) |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HEPH | hephaestin |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) |
| IMP4 | IMP4, U3 small nucleolar ribonucleoprotein |
| IPO13 | importin 13 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KRT14 | keratin 14, type I |
| KRT6B | keratin 6B, type II |
| LCN2 | lipocalin 2 |
| LONP1 | lon peptidase 1, mitochondrial |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MCM7 | minichromosome maintenance complex component 7 |
| MMP7 | matrix metallopeptidase 7 |
| MRPS35 | mitochondrial ribosomal protein S35 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NOP16 | NOP16 nucleolar protein |
| OLFM4 | olfactomedin 4 |
| PCCB | propionyl CoA carboxylase, beta polypeptide |
| PDIA6 | protein disulfide isomerase family A, member 6 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLBD1 | phospholipase B domain containing 1 |
| PLN | phospholamban |
| PON2 | paraoxonase 2 |
| PRDX2 | peroxiredoxin 2 |
| PRR7 | proline rich 7 (synaptic) |
| PUF60 | poly-U binding splicing factor 60KDa |
| PWP1 | PWP1 homolog (S. cerevisiae) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RPIA | ribose 5-phosphate isomerase A |
| RRM2 | ribonucleotide reductase M2 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SMAGP | small cell adhesion glycoprotein |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TRAPPC3 | trafficking protein particle complex 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| TXNL4A | thioredoxin-like 4A |
| VDAC1 | voltage-dependent anion channel 1 |
