| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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270 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACKR3 | atypical chemokine receptor 3 |
| ADCY9 | adenylate cyclase 9 |
| ADD3 | adducin 3 (gamma) |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMDHD2 | amidohydrolase domain containing 2 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BEX4 | brain expressed, X-linked 4 |
| BLVRB | biliverdin reductase B |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BTG2 | BTG family, member 2 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CALD1 | caldesmon 1 |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD59 | CD59 molecule, complement regulatory protein |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CETN2 | centrin, EF-hand protein, 2 |
| CHMP2A | charged multivesicular body protein 2A |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTSB | cathepsin B |
| CTSV | cathepsin V |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| EFCAB14 | EF-hand calcium binding domain 14 |
| FADS3 | fatty acid desaturase 3 |
| FAM117A | family with sequence similarity 117, member A |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXO1 | forkhead box O1 |
| FOXO4 | forkhead box O4 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GLRX | glutaredoxin (thioltransferase) |
| GM2A | GM2 ganglioside activator |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GPM6B | glycoprotein M6B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HBP1 | HMG-box transcription factor 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H3H | histone cluster 1, H3h |
| HMOX1 | heme oxygenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| IRF9 | interferon regulatory factor 9 |
| JAG1 | jagged 1 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 |
| L1CAM | L1 cell adhesion molecule |
| LBH | limb bud and heart development |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LINC00094 | long intergenic non-protein coding RNA 94 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| LPIN1 | lipin 1 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MSN | moesin |
| MT1X | metallothionein 1X |
| MTSS1 | metastasis suppressor 1 |
| MXI1 | MAX interactor 1, dimerization protein |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NPC2 | Niemann-Pick disease, type C2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRCAM | neuronal cell adhesion molecule |
| OSBPL10 | oxysterol binding protein-like 10 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PEG10 | paternally expressed 10 |
| PLA2G15 | phospholipase A2, group XV |
| PLD3 | phospholipase D family, member 3 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRKCD | protein kinase C, delta |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB38 | RAB38, member RAS oncogene family |
| RABAC1 | Rab acceptor 1 (prenylated) |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RTN2 | reticulon 2 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGCE | sarcoglycan, epsilon |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SNAI2 | snail family zinc finger 2 |
| SNN | stannin |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPON1 | spondin 1, extracellular matrix protein |
| SQSTM1 | sequestosome 1 |
| SST | somatostatin |
| STAB1 | stabilin 1 |
| STXBP1 | syntaxin binding protein 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPP1 | tripeptidyl peptidase I |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UROD | uroporphyrinogen decarboxylase |
| VAT1 | vesicle amine transport 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WBP1L | WW domain binding protein 1-like |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF586 | zinc finger protein 586 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ADI1 | acireductone dioxygenase 1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANXA1 | annexin A1 |
| ANXA10 | annexin A10 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ATF5 | activating transcription factor 5 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BID | BH3 interacting domain death agonist |
| C1QBP | complement component 1, q subcomponent binding protein |
| CBFB | core-binding factor, beta subunit |
| CCNE2 | cyclin E2 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) |
| CD44 | CD44 molecule (Indian blood group) |
| CD58 | CD58 molecule |
| CDC25A | cell division cycle 25A |
| COMT | catechol-O-methyltransferase |
| CRYZ | crystallin, zeta (quinone reductase) |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CST3 | cystatin C |
| CTPS1 | CTP synthase 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBF4 | DBF4 zinc finger |
| DCTD | dCMP deaminase |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| DENND2D | DENN/MADD domain containing 2D |
| DKC1 | dyskeratosis congenita 1, dyskerin |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| ENO1 | enolase 1, (alpha) |
| ENOSF1 | enolase superfamily member 1 |
| EXOSC4 | exosome component 4 |
| FAM111A | family with sequence similarity 111, member A |
| FAM129A | family with sequence similarity 129, member A |
| FANCL | Fanconi anemia, complementation group L |
| FASN | fatty acid synthase |
| FERMT1 | fermitin family member 1 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FOSL1 | FOS-like antigen 1 |
| FPGS | folylpolyglutamate synthase |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GPX2 | glutathione peroxidase 2 |
| GSAP | gamma-secretase activating protein |
| GTPBP4 | GTP binding protein 4 |
| H2AFX | H2A histone family, member X |
| HMGB2 | high mobility group box 2 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIAA0020 | KIAA0020 |
| KIAA0101 | KIAA0101 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK10 | kallikrein-related peptidase 10 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT13 | keratin 13, type I |
| LAD1 | ladinin 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LCN2 | lipocalin 2 |
| LMNB1 | lamin B1 |
| LOXL1 | lysyl oxidase-like 1 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LYZ | lysozyme |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MBP | myelin basic protein |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM7 | minichromosome maintenance complex component 7 |
| MRPS30 | mitochondrial ribosomal protein S30 |
| MRPS35 | mitochondrial ribosomal protein S35 |
| MSRA | methionine sulfoxide reductase A |
| MTA1 | metastasis associated 1 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NBN | nibrin |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NOP16 | NOP16 nucleolar protein |
| ODC1 | ornithine decarboxylase 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLBD1 | phospholipase B domain containing 1 |
| PLCB4 | phospholipase C, beta 4 |
| PON2 | paraoxonase 2 |
| PPIF | peptidylprolyl isomerase F |
| PRC1 | protein regulator of cytokinesis 1 |
| PRR7 | proline rich 7 (synaptic) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB25 | RAB25, member RAS oncogene family |
| RAN | RAN, member RAS oncogene family |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RPIA | ribose 5-phosphate isomerase A |
| RPL10 | ribosomal protein L10 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRM2 | ribonucleotide reductase M2 |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A10 | S100 calcium binding protein A10 |
| S100P | S100 calcium binding protein P |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAGP | small cell adhesion glycoprotein |
| SMYD2 | SET and MYND domain containing 2 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SNRPD1 | small nuclear ribonucleoprotein D1 polypeptide 16kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPRR3 | small proline-rich protein 3 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
| SRM | spermidine synthase |
| SRPRB | signal recognition particle receptor, B subunit |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STC2 | stanniocalcin 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TESC | tescalcin |
| TEX10 | testis expressed 10 |
| TFF1 | trefoil factor 1 |
| TFRC | transferrin receptor |
| TMEM5 | transmembrane protein 5 |
| TMPO | thymopoietin |
| TP53 | tumor protein p53 |
| TRA2B | transformer 2 beta homolog (Drosophila) |
| TRIM29 | tripartite motif containing 29 |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN8 | tetraspanin 8 |
| TYMS | thymidylate synthetase |
| USP1 | ubiquitin specific peptidase 1 |
| XBP1 | X-box binding protein 1 |
| YBX3 | Y box binding protein 3 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF131 | zinc finger protein 131 |
