| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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229 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_LOVO_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABAT | 4-aminobutyrate aminotransferase |
| ACAA1 | acetyl-CoA acyltransferase 1 |
| ACOT7 | acyl-CoA thioesterase 7 |
| ADD3 | adducin 3 (gamma) |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATG2A | autophagy related 2A |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BAD | BCL2-associated agonist of cell death |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CA1 | carbonic anhydrase I |
| CA2 | carbonic anhydrase II |
| CADM1 | cell adhesion molecule 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) |
| CCND3 | cyclin D3 |
| CCNG2 | cyclin G2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLDN10 | claudin 10 |
| CNN3 | calponin 3, acidic |
| CORO1A | coronin, actin binding protein, 1A |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DUSP10 | dual specificity phosphatase 10 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF5A | eukaryotic translation initiation factor 5A |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| FADS3 | fatty acid desaturase 3 |
| FAM117A | family with sequence similarity 117, member A |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GLRX | glutaredoxin (thioltransferase) |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GOLGA7 | golgin A7 |
| GPX3 | glutathione peroxidase 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GUK1 | guanylate kinase 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HN1 | hematological and neurological expressed 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HSPA2 | heat shock 70kDa protein 2 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITM2C | integral membrane protein 2C |
| LEFTY1 | left-right determination factor 1 |
| LPIN1 | lipin 1 |
| LPXN | leupaxin |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN1 | mucolipin 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MGST3 | microsomal glutathione S-transferase 3 |
| MLF1 | myeloid leukemia factor 1 |
| MMD | monocyte to macrophage differentiation-associated |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1X | metallothionein 1X |
| MXI1 | MAX interactor 1, dimerization protein |
| NME7 | NME/NM23 family member 7 |
| NOSIP | nitric oxide synthase interacting protein |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase |
| PEG10 | paternally expressed 10 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLA2G15 | phospholipase A2, group XV |
| PLD3 | phospholipase D family, member 3 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKCD | protein kinase C, delta |
| PSENEN | presenilin enhancer gamma secretase subunit |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAD9A | RAD9 homolog A (S. pombe) |
| RAP2A | RAP2A, member of RAS oncogene family |
| RGS2 | regulator of G-protein signaling 2 |
| RIOK3 | RIO kinase 3 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SC5D | sterol-C5-desaturase |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SESN1 | sestrin 1 |
| SGCE | sarcoglycan, epsilon |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| SLC46A3 | solute carrier family 46, member 3 |
| SNX11 | sorting nexin 11 |
| SRPX | sushi-repeat containing protein, X-linked |
| SST | somatostatin |
| STX7 | syntaxin 7 |
| TBPL1 | TBP-like 1 |
| TKTL1 | transketolase-like 1 |
| TMEM41B | transmembrane protein 41B |
| TOB1 | transducer of ERBB2, 1 |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TSPAN13 | tetraspanin 13 |
| TUBA1A | tubulin, alpha 1a |
| TUBB2A | tubulin, beta 2A class IIa |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VIM | vimentin |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF586 | zinc finger protein 586 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| ZW10 | zw10 kinetochore protein |
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADIRF | adipogenesis regulatory factor |
| AGTR1 | angiotensin II receptor, type 1 |
| AKAP8 | A kinase (PRKA) anchor protein 8 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ANXA2 | annexin A2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASS1 | argininosuccinate synthase 1 |
| ATF1 | activating transcription factor 1 |
| ATF5 | activating transcription factor 5 |
| AUTS2 | autism susceptibility candidate 2 |
| BEX1 | brain expressed, X-linked 1 |
| BMP4 | bone morphogenetic protein 4 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C3 | complement component 3 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAST | calpastatin |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CCND1 | cyclin D1 |
| CST7 | cystatin F (leukocystatin) |
| CTPS1 | CTP synthase 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| EREG | epiregulin |
| ESR1 | estrogen receptor 1 |
| FAM60A | family with sequence similarity 60, member A |
| FOSL1 | FOS-like antigen 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GATA3 | GATA binding protein 3 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX2 | glutathione peroxidase 2 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HMGB2 | high mobility group box 2 |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
| JADE2 | jade family PHD finger 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KAZN | kazrin, periplakin interacting protein |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIAA0101 | KIAA0101 |
| KIAA0368 | KIAA0368 |
| KIF5B | kinesin family member 5B |
| KRT13 | keratin 13, type I |
| KRT15 | keratin 15, type I |
| KRT5 | keratin 5, type II |
| KRT6A | keratin 6A, type II |
| LTF | lactotransferrin |
| LYZ | lysozyme |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK13 | mitogen-activated protein kinase 13 |
| MECOM | MDS1 and EVI1 complex locus |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MICALL1 | MICAL-like 1 |
| MSMB | microseminoprotein, beta- |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUP62 | nucleoporin 62kDa |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLK1 | polo-like kinase 1 |
| PODXL | podocalyxin-like |
| POSTN | periostin, osteoblast specific factor |
| POU2AF1 | POU class 2 associating factor 1 |
| PSCA | prostate stem cell antigen |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RGS5 | regulator of G-protein signaling 5 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100P | S100 calcium binding protein P |
| SLAMF7 | SLAM family member 7 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORD | sorbitol dehydrogenase |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| STC2 | stanniocalcin 2 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYT1 | synaptotagmin I |
| TF | transferrin |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TLK1 | tousled-like kinase 1 |
| TLR4 | toll-like receptor 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRIM29 | tripartite motif containing 29 |
| TYMS | thymidylate synthetase |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VEGFA | vascular endothelial growth factor A |
| VSNL1 | visinin-like 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
