| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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178 genes differentially expressed following the BRD-K69840642_HDAC6 inhibitor ISOX_NCIH596_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ACOT7 | acyl-CoA thioesterase 7 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADCY9 | adenylate cyclase 9 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ASRGL1 | asparaginase like 1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CA2 | carbonic anhydrase II |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) |
| CCNG2 | cyclin G2 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD9 | CD9 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHGB | chromogranin B |
| CLIC4 | chloride intracellular channel 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| EFNB2 | ephrin-B2 |
| EPAS1 | endothelial PAS domain protein 1 |
| EZR | ezrin |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FOXO4 | forkhead box O4 |
| GRN | granulin |
| GSN | gelsolin |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IER3 | immediate early response 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 |
| ITM2C | integral membrane protein 2C |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KIAA0226L | KIAA0226-like |
| KLHL24 | kelch-like family member 24 |
| L1CAM | L1 cell adhesion molecule |
| LOC100505650 | uncharacterized LOC100505650 |
| MAGED2 | melanoma antigen family D2 |
| MAP7 | microtubule-associated protein 7 |
| MEF2C | myocyte enhancer factor 2C |
| NAGK | N-acetylglucosamine kinase |
| NEFL | neurofilament, light polypeptide |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NOSIP | nitric oxide synthase interacting protein |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PEG10 | paternally expressed 10 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PLA2G15 | phospholipase A2, group XV |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAP1GAP | RAP1 GTPase activating protein |
| RBPMS | RNA binding protein with multiple splicing |
| RHOB | ras homolog family member B |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SORT1 | sortilin 1 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| STXBP1 | syntaxin binding protein 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSPAN13 | tetraspanin 13 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
| ANXA1 | annexin A1 |
| AURKA | aurora kinase A |
| BAG2 | BCL2-associated athanogene 2 |
| BEX1 | brain expressed, X-linked 1 |
| C1R | complement component 1, r subcomponent |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CBR3 | carbonyl reductase 3 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD58 | CD58 molecule |
| CELF2 | CUGBP, Elav-like family member 2 |
| CFH | complement factor H |
| CTBP1 | C-terminal binding protein 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCTD | dCMP deaminase |
| DEK | DEK proto-oncogene |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP22 | dual specificity phosphatase 22 |
| DUSP4 | dual specificity phosphatase 4 |
| DUT | deoxyuridine triphosphatase |
| EIF5A | eukaryotic translation initiation factor 5A |
| EMG1 | EMG1 N1-specific pseudouridine methyltransferase |
| EMP3 | epithelial membrane protein 3 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM57A | family with sequence similarity 57, member A |
| FOSL1 | FOS-like antigen 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GATAD1 | GATA zinc finger domain containing 1 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GPM6B | glycoprotein M6B |
| GSAP | gamma-secretase activating protein |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HOXA10 | homeobox A10 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDM5D | lysine (K)-specific demethylase 5D |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIAA0368 | KIAA0368 |
| KRT14 | keratin 14, type I |
| KRT15 | keratin 15, type I |
| KRT17 | keratin 17, type I |
| KRT5 | keratin 5, type II |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| KYNU | kynureninase |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIPT1 | lipoyltransferase 1 |
| LTF | lactotransferrin |
| MAPK6 | mitogen-activated protein kinase 6 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| PGC | progastricsin (pepsinogen C) |
| PIR | pirin (iron-binding nuclear protein) |
| PRR7 | proline rich 7 (synaptic) |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB13 | RAB13, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| S100A7 | S100 calcium binding protein A7 |
| SFN | stratifin |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E |
| SORD | sorbitol dehydrogenase |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TCERG1 | transcription elongation regulator 1 |
| TF | transferrin |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM45A | transmembrane protein 45A |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRIM16 | tripartite motif containing 16 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN8 | tetraspanin 8 |
| TUBB6 | tubulin, beta 6 class V |
| TXNDC9 | thioredoxin domain containing 9 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| USP1 | ubiquitin specific peptidase 1 |
| USP22 | ubiquitin specific peptidase 22 |
| WBP5 | WW domain binding protein 5 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZIC1 | Zic family member 1 |
