BRD-K69888333_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K69888333_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
ANXA4 annexin A4
C6ORF62 chromosome 6 open reading frame 62
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD52 CD52 molecule
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
DDIT4 DNA-damage-inducible transcript 4
EFNB2 ephrin-B2
EIF5A eukaryotic translation initiation factor 5A
FHL1 four and a half LIM domains 1
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
MCAM melanoma cell adhesion molecule
MGP matrix Gla protein
PRSS3 protease, serine, 3
SFN stratifin
SKAP2 src kinase associated phosphoprotein 2
TSPAN8 tetraspanin 8
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA2 carbonic anhydrase II
JADE2 jade family PHD finger 2
LTF lactotransferrin
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNC tenascin C