| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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273 genes differentially expressed following the BRD-K69932463_AZD-8055_MCF10A_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ADIRF | adipogenesis regulatory factor |
| AHNAK | AHNAK nucleoprotein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMOTL2 | angiomotin like 2 |
| ANXA4 | annexin A4 |
| ANXA5 | annexin A5 |
| APOD | apolipoprotein D |
| ATP9A | ATPase, class II, type 9A |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CAMLG | calcium modulating ligand |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD9 | CD9 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CFB | complement factor B |
| CFD | complement factor D (adipsin) |
| CIRBP | cold inducible RNA binding protein |
| COL6A1 | collagen, type VI, alpha 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTSK | cathepsin K |
| DARS | aspartyl-tRNA synthetase |
| DCN | decorin |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EGFR | epidermal growth factor receptor |
| EMP1 | epithelial membrane protein 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FADS3 | fatty acid desaturase 3 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBLN1 | fibulin 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL1 | four and a half LIM domains 1 |
| FZD7 | frizzled class receptor 7 |
| G0S2 | G0/G1 switch 2 |
| GAS6 | growth arrest-specific 6 |
| GDI1 | GDP dissociation inhibitor 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPX3 | glutathione peroxidase 3 |
| GPX4 | glutathione peroxidase 4 |
| GRN | granulin |
| GSN | gelsolin |
| HBP1 | HMG-box transcription factor 1 |
| HMGA2 | high mobility group AT-hook 2 |
| IDS | iduronate 2-sulfatase |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1R1 | interleukin 1 receptor, type I |
| IRS1 | insulin receptor substrate 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGAV | integrin, alpha V |
| ITGB4 | integrin, beta 4 |
| ITGB5 | integrin, beta 5 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| JAG1 | jagged 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5B | lysine (K)-specific demethylase 5B |
| LAMC2 | laminin, gamma 2 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LEPR | leptin receptor |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOXL1 | lysyl oxidase-like 1 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| MGLL | monoglyceride lipase |
| MT1F | metallothionein 1F |
| MTMR11 | myotubularin related protein 11 |
| MTSS1 | metastasis suppressor 1 |
| MUC1 | mucin 1, cell surface associated |
| NCF2 | neutrophil cytosolic factor 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OPTN | optineurin |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PGLS | 6-phosphogluconolactonase |
| PHF20 | PHD finger protein 20 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLXNB2 | plexin B2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPL | periplakin |
| PTK2B | protein tyrosine kinase 2 beta |
| RBKS | ribokinase |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFXN3 | sideroflexin 3 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| SULF1 | sulfatase 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TNS3 | tensin 3 |
| TPP1 | tripeptidyl peptidase I |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VAT1 | vesicle amine transport 1 |
| VCAN | versican |
| VNN1 | vanin 1 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WDR13 | WD repeat domain 13 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| AURKA | aurora kinase A |
| BAG2 | BCL2-associated athanogene 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BRCA1 | breast cancer 1, early onset |
| C1QBP | complement component 1, q subcomponent binding protein |
| CCNA2 | cyclin A2 |
| CCNB1 | cyclin B1 |
| CCNF | cyclin F |
| CD320 | CD320 molecule |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDK1 | cyclin-dependent kinase 1 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYCS | cytochrome c, somatic |
| DBF4 | DBF4 zinc finger |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPDC1 | DEP domain containing 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EXO1 | exonuclease 1 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEN1 | flap structure-specific endonuclease 1 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| GAL | galanin/GMAP prepropeptide |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GCH1 | GTP cyclohydrolase 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFZ | H2A histone family, member Z |
| HCP5 | HLA complex P5 (non-protein coding) |
| HIST1H4C | histone cluster 1, H4c |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| IFI44 | interferon-induced protein 44 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KIAA0101 | KIAA0101 |
| KIF20A | kinesin family member 20A |
| LBR | lamin B receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LRRC59 | leucine rich repeat containing 59 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MALL | mal, T-cell differentiation protein-like |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MLEC | malectin |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NLRP2 | NLR family, pyrin domain containing 2 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NPY | neuropeptide Y |
| NUP107 | nucleoporin 107kDa |
| NUP98 | nucleoporin 98kDa |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHGDH | phosphoglycerate dehydrogenase |
| PLAC8 | placenta-specific 8 |
| PLK1 | polo-like kinase 1 |
| PLS1 | plastin 1 |
| PNP | purine nucleoside phosphorylase |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PRC1 | protein regulator of cytokinesis 1 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRPF4 | pre-mRNA processing factor 4 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PSPH | phosphoserine phosphatase |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAD51C | RAD51 paralog C |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RPA2 | replication protein A2, 32kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SORD | sorbitol dehydrogenase |
| SRSF3 | serine/arginine-rich splicing factor 3 |
| STMN1 | stathmin 1 |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TESC | tescalcin |
| TFAM | transcription factor A, mitochondrial |
| TMEM194A | transmembrane protein 194A |
| TMEM38B | transmembrane protein 38B |
| TMEM97 | transmembrane protein 97 |
| TMPO | thymopoietin |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSPAN8 | tetraspanin 8 |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 |
| VDAC3 | voltage-dependent anion channel 3 |
| VRK1 | vaccinia related kinase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
