| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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203 genes differentially expressed following the BRD-K69932463_AZD-8055_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| AGR2 | anterior gradient 2 |
| AIM1 | absent in melanoma 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| BCL2L1 | BCL2-like 1 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CAMLG | calcium modulating ligand |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDK7 | cyclin-dependent kinase 7 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CYTH1 | cytohesin 1 |
| DAPK1 | death-associated protein kinase 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DUSP5 | dual specificity phosphatase 5 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFNA1 | ephrin-A1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF3D | eukaryotic translation initiation factor 3, subunit D |
| EIF4B | eukaryotic translation initiation factor 4B |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FOXO3 | forkhead box O3 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GDF15 | growth differentiation factor 15 |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GLUL | glutamate-ammonia ligase |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H2AC | histone cluster 1, H2ac |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IRS1 | insulin receptor substrate 1 |
| JADE2 | jade family PHD finger 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KRT18 | keratin 18, type I |
| KRT19 | keratin 19, type I |
| LAMB3 | laminin, beta 3 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LINC00342 | long intergenic non-protein coding RNA 342 |
| LOC100272216 | uncharacterized LOC100272216 |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MLPH | melanophilin |
| MVP | major vault protein |
| MYOF | myoferlin |
| MYRF | myelin regulatory factor |
| NBPF10 | neuroblastoma breakpoint family, member 10 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OBSL1 | obscurin-like 1 |
| PLAU | plasminogen activator, urokinase |
| PLXNB2 | plexin B2 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa |
| PPL | periplakin |
| PTX3 | pentraxin 3, long |
| RAP1GAP | RAP1 GTPase activating protein |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RRAD | Ras-related associated with diabetes |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
| SECISBP2L | SECIS binding protein 2-like |
| SFRP4 | secreted frizzled-related protein 4 |
| SMAD3 | SMAD family member 3 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPATA7 | spermatogenesis associated 7 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| SVIL | supervillin |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYNJ2 | synaptojanin 2 |
| TANK | TRAF family member-associated NFKB activator |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMC5 | transmembrane channel-like 5 |
| TOB2 | transducer of ERBB2, 2 |
| WASL | Wiskott-Aldrich syndrome-like |
| XIST | X inactive specific transcript (non-protein coding) |
| ZNF277 | zinc finger protein 277 |
| Symbol | Name |
|---|---|
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AK1 | adenylate kinase 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDOC | aldolase C, fructose-bisphosphate |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| AQP1 | aquaporin 1 (Colton blood group) |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| AURKA | aurora kinase A |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BMP2 | bone morphogenetic protein 2 |
| CALR | calreticulin |
| CCNA2 | cyclin A2 |
| CCND3 | cyclin D3 |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDK1 | cyclin-dependent kinase 1 |
| CDK2 | cyclin-dependent kinase 2 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPU | centromere protein U |
| CIT | citron rho-interacting serine/threonine kinase |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| COL1A2 | collagen, type I, alpha 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTPS1 | CTP synthase 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYCS | cytochrome c, somatic |
| DCN | decorin |
| EBP | emopamil binding protein (sterol isomerase) |
| EDNRB | endothelin receptor type B |
| EIF4E | eukaryotic translation initiation factor 4E |
| FABP7 | fatty acid binding protein 7, brain |
| FAS | Fas cell surface death receptor |
| FBN2 | fibrillin 2 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FGF2 | fibroblast growth factor 2 (basic) |
| FHL1 | four and a half LIM domains 1 |
| FOXG1 | forkhead box G1 |
| FRZB | frizzled-related protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAL | galanin/GMAP prepropeptide |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GNAS | GNAS complex locus |
| GPM6B | glycoprotein M6B |
| GPX3 | glutathione peroxidase 3 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMGB1 | high mobility group box 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 |
| HSPA1A | heat shock 70kDa protein 1A |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFRD2 | interferon-related developmental regulator 2 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| KRT14 | keratin 14, type I |
| KRT5 | keratin 5, type II |
| KRT6B | keratin 6B, type II |
| LBR | lamin B receptor |
| LPL | lipoprotein lipase |
| MALT1 | MALT1 paracaspase |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MELK | maternal embryonic leucine zipper kinase |
| MOXD1 | monooxygenase, DBH-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 |
| PCDH9 | protocadherin 9 |
| PDZK1 | PDZ domain containing 1 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| POSTN | periostin, osteoblast specific factor |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTTG1 | pituitary tumor-transforming 1 |
| RCAN1 | regulator of calcineurin 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RRM2 | ribonucleotide reductase M2 |
| RTN1 | reticulon 1 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRPRB | signal recognition particle receptor, B subunit |
| STMN1 | stathmin 1 |
| TDO2 | tryptophan 2,3-dioxygenase |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM45A | transmembrane protein 45A |
| TMEM47 | transmembrane protein 47 |
| TMPO | thymopoietin |
| TMX2 | thioredoxin-related transmembrane protein 2 |
| TNC | tenascin C |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TPX2 | TPX2, microtubule-associated |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| TYRP1 | tyrosinase-related protein 1 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VBP1 | von Hippel-Lindau binding protein 1 |
| WSB2 | WD repeat and SOCS box containing 2 |
| ZWINT | ZW10 interacting kinetochore protein |
