BRD-K70642949_GSK-2334470_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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75 genes differentially expressed following the BRD-K70642949_GSK-2334470_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BASP1 brain abundant, membrane attached signal protein 1
C9ORF3 chromosome 9 open reading frame 3
CAST calpastatin
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHL1 cell adhesion molecule L1-like
CHN1 chimerin 1
CORO1A coronin, actin binding protein, 1A
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
EBP emopamil binding protein (sterol isomerase)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
GREM1 gremlin 1, DAN family BMP antagonist
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IL7R interleukin 7 receptor
ITM2C integral membrane protein 2C
MAN1C1 mannosidase, alpha, class 1C, member 1
MEIS1 Meis homeobox 1
MSLN mesothelin
MUC4 mucin 4, cell surface associated
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TRAC T cell receptor alpha constant
TRBC1 T cell receptor beta constant 1
TSPAN8 tetraspanin 8
TTC3 tetratricopeptide repeat domain 3
VDAC1 voltage-dependent anion channel 1
WRB tryptophan rich basic protein
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANO1 anoctamin 1, calcium activated chloride channel
APOC1 apolipoprotein C-I
C10ORF10 chromosome 10 open reading frame 10
CD36 CD36 molecule (thrombospondin receptor)
CLCA2 chloride channel accessory 2
CLDN18 claudin 18
CST6 cystatin E/M
CX3CL1 chemokine (C-X3-C motif) ligand 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
GAL galanin/GMAP prepropeptide
HEBP1 heme binding protein 1
HK2 hexokinase 2
KRT14 keratin 14, type I
KRT17 keratin 17, type I
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
NLRP2 NLR family, pyrin domain containing 2
PIP prolactin-induced protein
PROM1 prominin 1
RAB38 RAB38, member RAS oncogene family
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
SPRR1B small proline-rich protein 1B
STXBP2 syntaxin binding protein 2
TMEM45A transmembrane protein 45A
TNC tenascin C
TPM4 tropomyosin 4
VCAN versican
ZNF589 zinc finger protein 589