| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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142 genes differentially expressed following the BRD-K70748405_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADORA2B | adenosine A2b receptor |
| ARG2 | arginase 2 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| CA12 | carbonic anhydrase XII |
| CAST | calpastatin |
| CCDC86 | coiled-coil domain containing 86 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CHMP4A | charged multivesicular body protein 4A |
| CHN2 | chimerin 2 |
| CKB | creatine kinase, brain |
| CLIC4 | chloride intracellular channel 4 |
| CPM | carboxypeptidase M |
| DCLK1 | doublecortin-like kinase 1 |
| DCN | decorin |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DPP4 | dipeptidyl-peptidase 4 |
| FAM134B | family with sequence similarity 134, member B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HOXB6 | homeobox B6 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL1R1 | interleukin 1 receptor, type I |
| ITM2C | integral membrane protein 2C |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| L1CAM | L1 cell adhesion molecule |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LUM | lumican |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MSLN | mesothelin |
| MSMB | microseminoprotein, beta- |
| MTSS1 | metastasis suppressor 1 |
| NEFL | neurofilament, light polypeptide |
| NELL2 | NEL-like 2 (chicken) |
| NPTX2 | neuronal pentraxin II |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| OLFML2A | olfactomedin-like 2A |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PON2 | paraoxonase 2 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| RAD21 | RAD21 homolog (S. pombe) |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RTN2 | reticulon 2 |
| SDC2 | syndecan 2 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SNAI2 | snail family zinc finger 2 |
| SNX13 | sorting nexin 13 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM100 | transmembrane protein 100 |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TROVE2 | TROVE domain family, member 2 |
| TSPAN12 | tetraspanin 12 |
| TUSC3 | tumor suppressor candidate 3 |
| VEGFA | vascular endothelial growth factor A |
| WDR7 | WD repeat domain 7 |
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| AK4 | adenylate kinase 4 |
| ANXA3 | annexin A3 |
| APOA1 | apolipoprotein A-I |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| AUTS2 | autism susceptibility candidate 2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CD59 | CD59 molecule, complement regulatory protein |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CKAP4 | cytoskeleton-associated protein 4 |
| CLIC3 | chloride intracellular channel 3 |
| CLU | clusterin |
| COL5A1 | collagen, type V, alpha 1 |
| CRCT1 | cysteine-rich C-terminal 1 |
| CSTA | cystatin A (stefin A) |
| CTSZ | cathepsin Z |
| DHCR7 | 7-dehydrocholesterol reductase |
| DICER1 | dicer 1, ribonuclease type III |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| ECM1 | extracellular matrix protein 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FLNA | filamin A, alpha |
| G0S2 | G0/G1 switch 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GPX2 | glutathione peroxidase 2 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HOPX | HOP homeobox |
| IFI44L | interferon-induced protein 44-like |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IL1RN | interleukin 1 receptor antagonist |
| KYNU | kynureninase |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LDLR | low density lipoprotein receptor |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MEIS1 | Meis homeobox 1 |
| MGAM | maltase-glucoamylase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MSMO1 | methylsterol monooxygenase 1 |
| MUC1 | mucin 1, cell surface associated |
| NEBL | nebulette |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PIP | prolactin-induced protein |
| PODXL | podocalyxin-like |
| PROM1 | prominin 1 |
| QDPR | quinoid dihydropteridine reductase |
| RDX | radixin |
| RPL37A | ribosomal protein L37a |
| RPS11 | ribosomal protein S11 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| S100A12 | S100 calcium binding protein A12 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDC1 | syndecan 1 |
| SELL | selectin L |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SQLE | squalene epoxidase |
| TLR4 | toll-like receptor 4 |
| TSTA3 | tissue specific transplantation antigen P35B |
| VWF | von Willebrand factor |
