BRD-K70792160_Akt inhibitor X_A549_6.0_h_24.0_um Gene Set
Genes
51 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_A549_6.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ATP6V1C1
|
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
|
C6ORF62
|
chromosome 6 open reading frame 62
|
|
CD55
|
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
|
|
CYP1B1
|
cytochrome P450, family 1, subfamily B, polypeptide 1
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
|
DENND1B
|
DENN/MADD domain containing 1B
|
|
EPS8
|
epidermal growth factor receptor pathway substrate 8
|
|
FZD6
|
frizzled class receptor 6
|
|
GNPDA1
|
glucosamine-6-phosphate deaminase 1
|
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1
|
|
HMOX1
|
heme oxygenase 1
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
|
INSIG1
|
insulin induced gene 1
|
|
LRRC15
|
leucine rich repeat containing 15
|
|
MN1
|
meningioma (disrupted in balanced translocation) 1
|
|
PSMF1
|
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
VAT1
|
vesicle amine transport 1
|
decreased expression
| Symbol |
Name |
|
CCL2
|
chemokine (C-C motif) ligand 2
|
|
CFB
|
complement factor B
|
|
CHGB
|
chromogranin B
|
|
CHI3L2
|
chitinase 3-like 2
|
|
COL6A1
|
collagen, type VI, alpha 1
|
|
COL6A2
|
collagen, type VI, alpha 2
|
|
CRABP1
|
cellular retinoic acid binding protein 1
|
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
|
|
CXCL13
|
chemokine (C-X-C motif) ligand 13
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
|
CXCL5
|
chemokine (C-X-C motif) ligand 5
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
|
FRZB
|
frizzled-related protein
|
|
GABRE
|
gamma-aminobutyric acid (GABA) A receptor, epsilon
|
|
LCN2
|
lipocalin 2
|
|
MMP9
|
matrix metallopeptidase 9
|
|
MT1F
|
metallothionein 1F
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
|
OLFM4
|
olfactomedin 4
|
|
PDZK1IP1
|
PDZK1 interacting protein 1
|
|
PEG3
|
paternally expressed 3
|
|
PLAGL1
|
pleiomorphic adenoma gene-like 1
|
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta
|
|
PTGDS
|
prostaglandin D2 synthase 21kDa (brain)
|
|
RAI2
|
retinoic acid induced 2
|
|
RARRES1
|
retinoic acid receptor responder (tazarotene induced) 1
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
|
SFRP1
|
secreted frizzled-related protein 1
|
|
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2
|
