| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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112 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_A673_6.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTB | actin, beta |
| APOD | apolipoprotein D |
| CALML5 | calmodulin-like 5 |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CLCA2 | chloride channel accessory 2 |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CLIC4 | chloride intracellular channel 4 |
| CRYM | crystallin, mu |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DAPK1 | death-associated protein kinase 1 |
| EEF2 | eukaryotic translation elongation factor 2 |
| EGFR | epidermal growth factor receptor |
| EIF5A | eukaryotic translation initiation factor 5A |
| FABP7 | fatty acid binding protein 7, brain |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GATA3 | GATA binding protein 3 |
| GLUL | glutamate-ammonia ligase |
| GSTA4 | glutathione S-transferase alpha 4 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| INSIG1 | insulin induced gene 1 |
| ITM2B | integral membrane protein 2B |
| KRT14 | keratin 14, type I |
| KRT17 | keratin 17, type I |
| KRT6A | keratin 6A, type II |
| KRT6B | keratin 6B, type II |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LTF | lactotransferrin |
| MAP7 | microtubule-associated protein 7 |
| MCOLN1 | mucolipin 1 |
| MMP7 | matrix metallopeptidase 7 |
| MSMO1 | methylsterol monooxygenase 1 |
| MTSS1 | metastasis suppressor 1 |
| NRN1 | neuritin 1 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RNF167 | ring finger protein 167 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SPRR1A | small proline-rich protein 1A |
| SPRR1B | small proline-rich protein 1B |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SQLE | squalene epoxidase |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STAP2 | signal transducing adaptor family member 2 |
| STX1A | syntaxin 1A (brain) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TXNIP | thioredoxin interacting protein |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ATMIN | ATM interactor |
| CCNE2 | cyclin E2 |
| CLU | clusterin |
| COL8A2 | collagen, type VIII, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CPE | carboxypeptidase E |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRP | C-reactive protein, pentraxin-related |
| CYBA | cytochrome b-245, alpha polypeptide |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EPHA3 | EPH receptor A3 |
| FABP1 | fatty acid binding protein 1, liver |
| FOXF1 | forkhead box F1 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HBB | hemoglobin, beta |
| ICAM2 | intercellular adhesion molecule 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ISG15 | ISG15 ubiquitin-like modifier |
| KRT19 | keratin 19, type I |
| KRT8 | keratin 8, type II |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MGLL | monoglyceride lipase |
| MGP | matrix Gla protein |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NGRN | neugrin, neurite outgrowth associated |
| ODC1 | ornithine decarboxylase 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCP4 | Purkinje cell protein 4 |
| PDE10A | phosphodiesterase 10A |
| PEG10 | paternally expressed 10 |
| PLK1 | polo-like kinase 1 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PXDN | peroxidasin |
| RPN1 | ribophorin I |
| SGCE | sarcoglycan, epsilon |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SMNDC1 | survival motor neuron domain containing 1 |
| SRGN | serglycin |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TFRC | transferrin receptor |
| TLR4 | toll-like receptor 4 |
| TOB1 | transducer of ERBB2, 1 |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| ZNF586 | zinc finger protein 586 |
