BRD-K70792160_Akt inhibitor X_HCC515_24.0_h_24.0_um Gene Set
Genes
20 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_HCC515_24.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
CA12
|
carbonic anhydrase XII
|
|
CAST
|
calpastatin
|
|
CYP51A1
|
cytochrome P450, family 51, subfamily A, polypeptide 1
|
|
DHCR24
|
24-dehydrocholesterol reductase
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
|
INSIG1
|
insulin induced gene 1
|
|
MLPH
|
melanophilin
|
|
MTSS1
|
metastasis suppressor 1
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
SCGB2A2
|
secretoglobin, family 2A, member 2
|
|
TFPI
|
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
COL14A1
|
collagen, type XIV, alpha 1
|
|
EFEMP1
|
EGF containing fibulin-like extracellular matrix protein 1
|
|
IGFBP3
|
insulin-like growth factor binding protein 3
|
|
PRDX2
|
peroxiredoxin 2
|
|
RBP1
|
retinol binding protein 1, cellular
|
|
TSPAN13
|
tetraspanin 13
|
